Ateeq Bushra, Bhatia Vipul, Goel Sakshi
Molecular Oncology Laboratory, Department of Biological Sciences and Bioengineering, Indian Institute of Technology, Kanpur, Uttar Pradesh 208016, India.
Molecular Oncology Laboratory, Department of Biological Sciences and Bioengineering, Indian Institute of Technology, Kanpur, Uttar Pradesh 208016, India.
Trends Cancer. 2016 Mar;2(3):116-120. doi: 10.1016/j.trecan.2016.01.005. Epub 2016 Feb 11.
Recent molecular characterization of prostate cancer (PCa) identified novel genetic aberrations and disease subtypes. The frequencies of molecular aberrations show racial disparity. Clinical strategies and targeted therapies embracing these racial differences are required. Here we discuss ethnic differences in genetic alterations and their impact on the susceptibility, progression, and treatment of prostate cancer.
近期对前列腺癌(PCa)的分子特征分析发现了新的基因异常和疾病亚型。分子异常的频率存在种族差异。需要采取考虑到这些种族差异的临床策略和靶向治疗方法。在此,我们讨论基因改变中的种族差异及其对前列腺癌易感性、进展和治疗的影响。