Plant Sciences Division, Research School of Biology, The Australian National University, Canberra 2601, Australia.
School of Chemistry and Molecular Biosciences, Institute for Molecular Bioscience and Australian Infectious Diseases Research Centre, University of Queensland, Brisbane, Australia.
Trends Plant Sci. 2017 Oct;22(10):871-879. doi: 10.1016/j.tplants.2017.06.013. Epub 2017 Jul 22.
The members of the pathogenesis-related protein 1 (PR-1) family are among the most abundantly produced proteins in plants on pathogen attack, and PR-1 gene expression has long been used as a marker for salicylic acid-mediated disease resistance. However, despite considerable interest over several decades, their requirement and role in plant defence remains poorly understood. Recent reports have emerged demonstrating that PR-1 proteins possess sterol-binding activity, harbour an embedded defence signalling peptide, and are targeted by plant pathogens during host infection. These studies have re-energised the field and provided long-awaited insights into a possible PR-1 function. Here we review the current status of PR-1 proteins and discuss how these recent advances shed light on putative roles for these enigmatic proteins.
植物受到病原体攻击时，病程相关蛋白 1（PR-1）家族的成员是产生量最丰富的蛋白之一，PR-1 基因的表达长期以来一直被用作水杨酸介导的抗病性的标志物。然而，尽管几十年来人们对此非常感兴趣，但它们在植物防御中的需求和作用仍知之甚少。最近的报告表明，PR-1 蛋白具有固醇结合活性，包含一个嵌入式防御信号肽，并且在宿主感染期间被植物病原体靶向。这些研究重新激发了该领域的研究兴趣，并为 PR-1 蛋白的可能功能提供了期待已久的见解。在这里，我们回顾了 PR-1 蛋白的现状，并讨论了这些最新进展如何阐明这些神秘蛋白的假定作用。
