Amin Alpesh N, Ganapathy Vaidyanathan, Roughley Adam, Small Mark
Department of Medicine, University of California, Irvine, USA.
Global Health Economics & Outcomes Research, Sunovion Pharmaceuticals Inc, Marlborough, USA.
Patient Prefer Adherence. 2017 Jul 12;11:1205-1212. doi: 10.2147/PPA.S140139. eCollection 2017.
Improper use of bronchodilators is associated with poor disease control, nonadherence to long-term therapy, and poor clinical outcomes. Our current understanding of factors associated with correct inhaler use and adherence is limited. We measured physician-and patient-reported confidence in device usage and associations with treatment adherence and COPD-related health status.
This was an analysis of a US observational, point-in-time survey of physicians and patients. Physicians who met study eligibility criteria completed surveys for 5 consecutive, eligible patients who were then invited to respond to questionnaires. We assessed patient demographics, type of prescribed inhaler device(s), device training, COPD severity, comorbidities, physician-and patient self-reported confidence in device usage, treatment adherence, and health status.
Completed questionnaires for 373 patients were provided by 134 physicians. Complete confidence in device usage was observed for 22% and 17% of patients as reported by patients and physicians, respectively. Greater confidence was associated with higher self-reported adherence to inhaler usage. Physicians were more likely than patients to report lower levels of patient confidence in device usage. High physician- and patient-reported confidence were associated with more favorable health status. Predictors of confidence in device usage included fewer comorbidities, no depression, and higher education levels.
Low confidence in inhaler usage was associated with lower adherence and poor COPD-related health status. Choice of inhaler device tailored to patients' ability to use specific devices and ongoing education to support optimal inhaler usage may improve patient confidence and enhance both adherence and health status.
支气管扩张剂使用不当与疾病控制不佳、不坚持长期治疗以及临床预后不良相关。我们目前对与正确吸入器使用及依从性相关因素的了解有限。我们测量了医生和患者报告的对器械使用的信心以及与治疗依从性和慢性阻塞性肺疾病(COPD)相关健康状况的关联。
这是一项对美国医生和患者的观察性、即时调查的分析。符合研究纳入标准的医生为连续5名符合条件的患者完成调查问卷,这些患者随后被邀请回答问卷。我们评估了患者的人口统计学特征、所开具吸入器器械的类型、器械培训、COPD严重程度、合并症、医生和患者自我报告的对器械使用的信心、治疗依从性以及健康状况。
134名医生提供了373名患者的完整调查问卷。患者和医生报告分别显示,22%和17%的患者对器械使用完全有信心。更高的信心与更高的自我报告的吸入器使用依从性相关。医生比患者更有可能报告患者对器械使用的信心水平较低。医生和患者报告的高信心与更有利的健康状况相关。器械使用信心的预测因素包括合并症较少、无抑郁以及教育水平较高。
对吸入器使用信心低与较低的依从性和较差的COPD相关健康状况有关。根据患者使用特定器械的能力量身定制吸入器器械的选择以及持续教育以支持最佳吸入器使用,可能会提高患者信心并增强依从性和健康状况。