Munegumi Toratane, Tanikawa Naoya
Naruto University of Education, Naruto, Tokushima, 772-8502, Japan.
Gifu Shotoku Gakuen University, Gifu-shi, Gifu, 501-6194, Japan.
Orig Life Evol Biosph. 2017 Sep;47(3):355-369. doi: 10.1007/s11084-017-9547-0. Epub 2017 Jul 26.
Asparagine and aspartic acid might have mutually transformed in the primordial hydrosphere of the earth, if ammonia and aspartic acid had existed in equilibrium. These amino acids seem to contribute to polypeptides, while the simple amino acids glycine and alanine easily form cyclic dipeptides and do not achieve long peptide chains. Asparagine-comprising dipeptides contribute some kinds of activation forms of dipeptides because these can polymerize faster than asparagine only. The new finding of polypeptide formation suggests a pathway of sequential polypeptides to evolve a diversity of polypeptides.
如果氨和天冬氨酸处于平衡状态，天冬酰胺和天冬氨酸可能在地球原始水圈中相互转化。这些氨基酸似乎有助于形成多肽，而简单氨基酸甘氨酸和丙氨酸很容易形成环状二肽，无法形成长肽链。含天冬酰胺的二肽有助于形成某些二肽激活形式，因为它们比仅天冬酰胺能更快聚合。多肽形成的新发现提示了一条连续多肽的途径，以演化出多样的多肽。
