Wu Yue, Zhu Liangfan, Luo Yun
Institute of Biomedical Manufacturing and Life Quality Engineering, School of Mechanical Engineering Shanghai Jiao Tong University, Shanghai, China.
Artif Organs. 2017 Nov;41(11):979-987. doi: 10.1111/aor.12888. Epub 2017 Jul 26.
The blood pump has become a possible solution to heart diseases. For the prevention of device failure and hemocompatibility problems, a rotary pump with suspended bearing is a preferred solution. In our previous work, a novel injection suspension method has been introduced to levitate the rotor. The suspension method is totally passive. This study aims to apply this suspension method to a double-suction pump, and the property of the pump was investigated using computational fluid dynamics (CFD) methods. The flow field of the pump is simulated based on the SST k-ω turbulent model. The characteristic curves of the pump were calculated. At the nominal working point of 5 L/min, 100 mm Hg, the suspension force acting on the rotor was detected, which could reach 0.46 N with a gap of 150 µm. We compared the pump with a previously developed single-suction injection pump to evaluate the blood compatibility of the double-suction design. The average scalar shear stress values were 3.13 Pa for the double-suction pump and 7.10 Pa for the single-suction pump. Larger volumes in the single-suction pump were exposed to shear stresses higher than 10 Pa. Thresholds for the von Willebrand factor cleavage, platelet activation, and hemolysis were defined to be 9 Pa, 50 Pa, and 150 Pa, respectively. The volume fractions for the double-suction pump are lower for all thresholds. The normalized index of hemolysis (NIH) values for the two pumps were calculated to be 0.008 g/100 L and 0.016 g/100 L. Results proved that the double-suction pump has a better hemocompatibility compared with the single-suction pump.
血泵已成为治疗心脏病的一种可能解决方案。为防止设备故障和血液相容性问题,带有悬浮轴承的旋转泵是首选解决方案。在我们之前的工作中,引入了一种新颖的注射悬浮方法来悬浮转子。该悬浮方法完全是被动的。本研究旨在将这种悬浮方法应用于双吸泵,并使用计算流体动力学(CFD)方法研究该泵的性能。基于SST k-ω湍流模型对泵的流场进行了模拟。计算了泵的特性曲线。在5 L/min、100 mmHg的额定工作点,检测到作用在转子上的悬浮力,间隙为150 µm时该力可达0.46 N。我们将该泵与之前开发的单吸注射泵进行了比较,以评估双吸设计的血液相容性。双吸泵的平均标量剪应力值为3.13 Pa,单吸泵为7.10 Pa。单吸泵中更大的体积暴露于高于10 Pa的剪应力下。血管性血友病因子裂解、血小板活化和溶血的阈值分别定义为9 Pa、50 Pa和150 Pa。对于所有阈值,双吸泵的体积分数都更低。计算得出两台泵的归一化溶血指数(NIH)值分别为0.008 g/100 L和0.016 g/100 L。结果证明,与单吸泵相比,双吸泵具有更好的血液相容性。