Zhang Yinglei, Zhu Xiangjia, He Wenwen, Jiang Yongxiang, Lu Yi
Department of Ophthalmology, Eye, Ear, Nose, and Throat Hospital of Fudan University Key Laboratory of Myopia, Ministry of Health Shanghai Key Laboratory of Visual Impairment and Restoration of Shanghai, Fudan University, Shanghai, China.
Medicine (Baltimore). 2017 Jul;96(30):e7353. doi: 10.1097/MD.0000000000007353.
To evaluate the visual outcomes of cataract surgery in patients with uveitis, and to determine risk factors for the recurrence of uveitis and postoperative complications.Eighty patients with uveitis who underwent phacoemulsification with intraocular lens (IOL) implantation were included in this retrospective study. We analyzed the following data: patient characteristics, medications used, visual acuity, and complications of cataract surgery.The mean ± standard deviation time from cataract surgery to the last visit was 20.8 ± 10.4 months. Best-corrected visual acuity improved significantly after surgery (P < .001). The visual outcome was worse in patients with Behçet disease than in patients with other etiologies of uveitis. Gender (P = .018) and IOL type (P = .020) were significantly associated with recurrent uveitis after surgery. The incidence of recurrent inflammation was not significantly different between patients who did or did not receive systemic therapy (P = .43). Perioperative systemic therapies (P = .011) and recurrent uveitis within 3 months of surgery (P = .043) were associated with posterior capsular opacification. Perioperative systemic therapies (P = .026) and recurrent uveitis after surgery (P = .006) were also significantly associated with cystoid macular edema.Patients with uveitis could benefit from cataract surgery. Patients with Behçet disease had worse postoperative prognosis than patients with other etiologies of uveitis. A heparin-surface-modified IOL may reduce the incidence of recurrent inflammation.
评估葡萄膜炎患者白内障手术的视觉效果,并确定葡萄膜炎复发和术后并发症的危险因素。本回顾性研究纳入了80例行超声乳化白内障吸除联合人工晶状体(IOL)植入术的葡萄膜炎患者。我们分析了以下数据:患者特征、所用药物、视力及白内障手术并发症。白内障手术至最后一次随访的平均时间±标准差为20.8±10.4个月。术后最佳矫正视力显著提高(P<0.001)。白塞病患者的视觉效果比其他病因的葡萄膜炎患者差。性别(P=0.018)和人工晶状体类型(P=0.020)与术后葡萄膜炎复发显著相关。接受或未接受全身治疗的患者炎症复发率无显著差异(P=0.43)。围手术期全身治疗(P=0.011)和术后3个月内葡萄膜炎复发(P=0.043)与后囊膜混浊有关。围手术期全身治疗(P=0.026)和术后葡萄膜炎复发(P=0.006)也与黄斑囊样水肿显著相关。葡萄膜炎患者可从白内障手术中获益。白塞病患者的术后预后比其他病因的葡萄膜炎患者差。肝素表面改性人工晶状体可能会降低炎症复发率。