Liu Ting, Zhu Xiaomin, Chen Kaijian, Bai Ji
Department of Ophthalmology, Daping Hospital and Research Institute of Surgery, Third Military Medical University, Chongqing, China.
Medicine (Baltimore). 2017 Jul;96(30):e7409. doi: 10.1097/MD.0000000000007409.
To evaluate the refractive outcomes of balanced salt solution infiltration during small-incision lenticule extraction (SMILE).This randomized prospective study enrolled 52 patients (104 eyes) with myopic astigmatism. Patients underwent SMILE to correct the myopic astigmatism in Daping Hospital of the Third Military Medical University between January and July 2013. One eye of each patient received traditional SMILE (control group) and the other received a modified SMILE procedure (liquid infiltration group). The corrected distance visual acuity (CDVA), postoperative uncorrected distance visual acuity (UDVA), refraction, wavefront aberration, intraocular pressure (IOP), modulation transfer function (MTF) cut-off frequency, and objective scattering index (OSI) were evaluated.UDVA in the liquid infiltration group was significantly higher than that in the control group at 1 day postoperatively, but not at 1 month after surgery. Moreover, OSI and MTF cut-off frequency in the liquid infiltration group were higher than those in the control group at early follow-up. However, no significant intergroup difference was observed in the OSI and MTF cut-off frequency at 3 months after surgery. In addition, the predictability was better in the liquid infiltration group than in the control group. The changes of horizontal coma in the liquid infiltration group were lesser than those in the control group. However, no intergroup difference was observed in the reduction of IOP at 1 month after surgery.The modified SMILE procedure results in better visual outcomes than did the traditional SMILE procedure when used for treating myopic astigmatism.
评估小切口透镜切除术（SMILE）中平衡盐溶液浸润的屈光效果。这项随机前瞻性研究纳入了52例近视散光患者（104只眼）。2013年1月至7月期间，患者在第三军医大学大坪医院接受SMILE手术以矫正近视散光。每位患者的一只眼接受传统SMILE手术（对照组），另一只眼接受改良SMILE手术（液体浸润组）。评估矫正远视力（CDVA）、术后裸眼远视力（UDVA）、屈光、波前像差、眼压（IOP）、调制传递函数（MTF）截止频率和客观散射指数（OSI）。液体浸润组术后1天的UDVA显著高于对照组，但术后1个月时无差异。此外，液体浸润组在早期随访时的OSI和MTF截止频率高于对照组。然而，术后3个月时，两组在OSI和MTF截止频率方面未观察到显著差异。另外，液体浸润组的可预测性优于对照组。液体浸润组水平彗差的变化小于对照组。然而，术后1个月时两组在眼压降低方面未观察到差异。用于治疗近视散光时，改良SMILE手术比传统SMILE手术能带来更好的视觉效果。
