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[用左旋咪唑免疫刺激抗毒反应在绵羊联合梭菌疫苗免疫中的试验]

[Trials of immunostimulation of an antitoxic response with levamisole in the immunization of sheep with a combined clostridial vaccine].

作者信息

Bineva I, Peĭchev B, Marinov M I

出版信息

Vet Med Nauki. 1986;23(4):35-8.

PMID:2874649
Abstract

Comparative investigations were carried out on the antibody level in test animals--sheep, vaccinated with a polyvaccine against C and D enterotoxemia and necrotic hepatitis as well as in combined application with Levamisol. It was found that with the use of the preparation the stimulation of immunogenesis with type D and necrotic hepatitis--type B antigens (included in the composition of the polyvaccine) was enhanced. No stimulation of immunogenesis with the type C specific antigen was found within the period of investigation. Immunity was better built up when the animals were treated with the combined product as compared with the controls, given the polyvaccine without Levamisol.

摘要

对试验动物绵羊进行了比较研究,这些绵羊接种了针对C型和D型肠毒血症以及坏死性肝炎的多价疫苗,以及与左旋咪唑联合使用的情况。结果发现,使用该制剂可增强D型和坏死性肝炎B型抗原(包含在多价疫苗成分中)对免疫发生的刺激作用。在研究期间未发现C型特异性抗原对免疫发生有刺激作用。与仅接种不含左旋咪唑的多价疫苗的对照组相比,使用联合产品治疗的动物能更好地建立免疫。

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