减肥手术后体重指数低于30的相关因素。

Factors Associated With Achieving a Body Mass Index of Less Than 30 After Bariatric Surgery.

作者信息

Varban Oliver A, Cassidy Ruth B, Bonham Aaron, Carlin Arthur M, Ghaferi Amir, Finks Jonathan F

机构信息

Department of Surgery, University of Michigan Health Systems, Ann Arbor.

Center for Healthcare Outcomes and Policy, University of Michigan, Ann Arbor.

出版信息

JAMA Surg. 2017 Nov 1;152(11):1058-1064. doi: 10.1001/jamasurg.2017.2348.

Abstract

IMPORTANCE

Achieving a body mass index (BMI, calculated as weight in kilograms divided by height in meters squared) of less than 30 is an important goal of bariatric surgery, given the increased risk for weight-related morbidity and mortality with a BMI above this threshold.

OBJECTIVE

To identify predictors for achieving a BMI of less than 30 after bariatric surgery.

DESIGN, SETTING, AND PARTICIPANTS: This retrospective study used data from the Michigan Bariatric Surgery Collaborative, a statewide quality improvement collaborative that uses a prospectively gathered clinical data registry. A total of 27 320 adults undergoing primary bariatric surgery between June 2006 and May 2015 at teaching and nonteaching hospitals in Michigan were included.

EXPOSURE

Bariatric surgery.

MAIN OUTCOMES AND MEASURES

Logistic regression was used to identify predictors for achieving a BMI of less than 30 at 1 year after surgery. Secondary outcome measures included 30-day postoperative complications and 1-year self-reported comorbidity remission.

RESULTS

A total of 9713 patients (36%; mean [SD] age, 46.9 [11.3] years; 16.6% male) achieved a BMI of less than 30 at 1 year after bariatric surgery. A significant predictor for achieving this goal was a preoperative BMI of less than 40 (odds ratio [OR], 12.88; 95% CI, 11.71-14.16; P < .001). Patients who had a sleeve gastrectomy, gastric bypass, or duodenal switch were more likely to achieve a BMI of less than 30 compared with those who underwent adjustable gastric banding (OR, 8.37 [95% CI, 7.44-9.43]; OR, 21.43 [95% CI, 18.98-24.19]; and OR, 82.93 [95% CI, 59.78-115.03], respectively; P < .001). Only 8.5% of patients with a BMI greater than 50 achieved a BMI of less than 30 after bariatric surgery. Patients who achieved a BMI of less than 30 had significantly higher reported rates of medication discontinuation for hyperlipidemia (60.7% vs 43.2%, P < .001), diabetes (insulin: 67.7% vs 50.0%, P < .001; oral medications: 78.5% vs 64.3%, P < .001), and hypertension (54.7% vs 34.6%, P < .001), as well as a significantly higher rate of sleep apnea remission (72.5% vs 49.3%, P < .001) and higher satisfaction rate (92.8% vs 78.0%, P < .001) compared with patients who did not.

CONCLUSIONS AND RELEVANCE

Patients with a preoperative BMI of less than 40 are more likely to achieve a BMI of less than 30 after bariatric surgery and are more likely to experience comorbidity remission. Policies and practice patterns that delay bariatric surgery until the BMI is 50 or greater can result in significantly inferior outcomes.

摘要

重要性

鉴于体重指数(BMI,计算方法为体重(千克)除以身高(米)的平方)高于30时与体重相关的发病和死亡风险增加,实现BMI低于30是减肥手术的一个重要目标。

目的

确定减肥手术后BMI达到低于30的预测因素。

设计、设置和参与者:这项回顾性研究使用了密歇根减肥手术协作组的数据,该协作组是一个全州范围的质量改进协作组织,使用前瞻性收集的临床数据登记处。纳入了2006年6月至2015年5月期间在密歇根州教学医院和非教学医院接受初次减肥手术的27320名成年人。

暴露因素

减肥手术。

主要结局和测量指标

采用逻辑回归分析确定术后1年BMI达到低于30的预测因素。次要结局指标包括术后30天并发症和1年自我报告的合并症缓解情况。

结果

共有9713名患者(36%;平均[标准差]年龄,46.9[11.3]岁;16.6%为男性)在减肥手术后1年BMI达到低于30。实现这一目标的一个显著预测因素是术前BMI低于40(优势比[OR],12.88;95%置信区间,11.71 - 14.16;P <.001)。与接受可调节胃束带手术的患者相比,接受袖状胃切除术、胃旁路手术或十二指肠转位手术的患者更有可能实现BMI低于30(OR分别为8.37[95%置信区间,7.44 - 9.43];OR为21.43[95%置信区间,18.9

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