Suppr超能文献

先天性上睑下垂患者的角膜断层扫描变化。

Changes of corneal tomography in patients with congenital blepharoptosis.

机构信息

Eye Center, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Zhejiang, China.

出版信息

Sci Rep. 2017 Jul 26;7(1):6580. doi: 10.1038/s41598-017-06823-7.

Abstract

The study aimed to evaluate the effect of drooped eyelid on corneal tomography in congenital blepharoptosis patients. Sixty-four patients with congenital blepharoptosis and 64 age- and sex- matched healthy subjects were included. According to the eyelid margin to corneal light reflex distance (MRD), eyes with congenital blepharoptosis were categorized as mild, moderate, or severe. The eyes were scanned using the rotating Scheimpflug camera. Increased topometric parameters were observed in moderate and severe blepharoptosis. Back corneal elevations at the thinnest point were significant higher for mild (P = 0.009), moderate (P < 0.001), and severe (P < 0.001) congenital blepharoptosis compared with controls. Maximum Ambrósio's relational thickness (ART) was decreased in eyes with severe blepharoptosis (P < 0.001). Fnal D values were significantly higher in moderate (P < 0.001) and severe blepharoptosis (P < 0.001) groups than that of controls. There were significant correlations between MRD and most corneal tomographic parameters. Our findings indicated there was a trend toward subclinical keratoconus-like changes in the corneas of congenital blepharoptosis, with the increase of ptosis severity.

摘要

本研究旨在评估先天性上睑下垂患者的眼睑下垂对角膜断层扫描的影响。共纳入 64 例先天性上睑下垂患者和 64 例年龄和性别匹配的健康对照者。根据睑缘至角膜光反射距离(MRD),将先天性上睑下垂患者分为轻度、中度和重度。采用旋转式Scheimpflug 相机对患者进行扫描。结果显示,中度和重度上睑下垂患者的角膜拓扑学参数增加。与对照组相比,轻度(P = 0.009)、中度(P < 0.001)和重度(P < 0.001)先天性上睑下垂患者的最薄处后角膜隆起明显更高。严重上睑下垂患者的最大 Ambrósio 相关厚度(ART)降低(P < 0.001)。中度(P < 0.001)和重度(P < 0.001)上睑下垂患者的最终 D 值明显高于对照组。MRD 与大多数角膜断层扫描参数之间存在显著相关性。本研究结果表明,随着上睑下垂程度的增加,先天性上睑下垂患者的角膜存在亚临床圆锥角膜样改变的趋势。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e7de/5529457/1318964e6475/41598_2017_6823_Fig1_HTML.jpg

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验