Arnold W, Altermatt H J, Arnold R, Gebbers J O, Laissue J
Arch Otolaryngol Head Neck Surg. 1986 Sep;112(9):934-7. doi: 10.1001/archotol.1986.03780090030004.
Certain epithelia of the human inner ear and human endolymphatic sac display somatostatin and/or somatostatin-like immunoreactivity. Histologic sections from 13 human temporal bones and from 15 endolymphatic sacs were studied using the unlabeled antibody peroxidase-antiperoxidase technique. The somatostatin and/or somatostatin-like immunoreactive cells were located exclusively in the covering epithelium of the spiral prominence and in the epithelium of the intermediate and rugosal part of the endolymphatic sac. In the epithelium of the spiral prominence and endolymphatic sac, secretory granules of the same size and appearance as those of intestinal or pancreatic somatostatin-producing cells were demonstrated ultrastructurally. The findings are consistent with a local exocrine, paracrine, and/or endocrine system of the inner ear.
人类内耳和内淋巴囊的某些上皮显示生长抑素和/或生长抑素样免疫反应性。使用未标记抗体过氧化物酶-抗过氧化物酶技术对13块人类颞骨和15个内淋巴囊的组织学切片进行了研究。生长抑素和/或生长抑素样免疫反应性细胞仅位于螺旋隆起的覆盖上皮以及内淋巴囊中间和皱襞部分的上皮中。在螺旋隆起和内淋巴囊的上皮中，超微结构显示出与肠道或胰腺产生生长抑素的细胞大小和外观相同的分泌颗粒。这些发现与内耳的局部外分泌、旁分泌和/或内分泌系统一致。
