尸检及组织采样程序。

Procedures of Necropsy and Tissue Sampling.

作者信息

Fiette Laurence, Slaoui Mohamed, Bauchet Anne-Laure

机构信息

IMMR, 42, Boulevard Jourdan, 75014, Paris, France.

Preclinical Safety, Sanofi R&D, 13, Quai Jules Guesde, 94403, Vitry-sur-Seine, France.

出版信息

Methods Mol Biol. 2017;1641:71-100. doi: 10.1007/978-1-4939-7172-5_3.

DOI:10.1007/978-1-4939-7172-5_3

PMID:28748458

Abstract

Necropsy is a major step of most studies using laboratory animals. During necropsy, tissue and organ noticeable grossly changes should be recorded and critical tissue samples may be stored for the subsequent evaluation. It is therefore important that the personnel in charge of this key experimental step to be adequately trained and aware of the study endpoints.

摘要

尸检是大多数使用实验动物的研究中的一个重要步骤。在尸检过程中，应记录明显的组织和器官大体变化，关键组织样本可保存用于后续评估。因此，负责这一关键实验步骤的人员接受充分培训并了解研究终点非常重要。