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组织病理学在尸检实践中的应用。

The use of histopathology in the practice of necropsy.

作者信息

Williams J O, Goddard M J, Gresham G A, Wyatt B A

机构信息

East Anglia Regional Clinical Audit Team, Clinical School, Addenbrooke's Hospital, Cambridge, UK.

出版信息

J Clin Pathol. 1997 Aug;50(8):695-8. doi: 10.1136/jcp.50.8.695.

DOI:10.1136/jcp.50.8.695
PMID:9301557
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC500124/
Abstract

AIM

To examine current practice and to establish criteria for the use of histopathology in necropsy practice.

METHODS

During an audit of necropsy reporting, consensus could not be reached about the use of routine histopathology. Therefore local guidelines were formulated and current practice was compared with these guidelines. Fifteen consecutive necropsies undertaken by each consultant were reviewed and the use of histopathology noted.

RESULTS

In general, the standard of necropsy reporting was reasonably high. Tissue was retained for histopathology in 25% of necropsies and 72% of these necropsy reports included a histopathology report. Using the guidelines, the assessors judged that histopathology might have been valuable in a further 19%. It was felt that routine histopathology would not have been helpful in determining the cause of death in the remaining 56%. The importance of the pathologist's clinical judgement in individual cases was stressed. At reaudit, nearly two years later, there was no significant change in practice, reflecting the lack of consensus.

CONCLUSIONS

Even when histopathology might contribute to finding the cause of death, it was not always done. However, the assumption that histology is invariably helpful in determining the cause of death is challenged.

摘要

目的

审视当前的做法,并确立尸检实践中组织病理学应用的标准。

方法

在一次尸检报告审核期间,对于常规组织病理学的应用无法达成共识。因此制定了当地指南,并将当前做法与这些指南进行比较。对每位会诊医生连续进行的15例尸检进行了回顾,并记录了组织病理学的应用情况。

结果

总体而言,尸检报告的标准相当高。25%的尸检保留了组织用于组织病理学检查,其中72%的尸检报告包含组织病理学报告。根据指南,评估人员判断在另外19%的尸检中组织病理学可能会有价值。认为在其余56%的尸检中常规组织病理学对确定死因没有帮助。强调了病理学家在个别病例中的临床判断的重要性。在将近两年后的重新审核中,实践没有显著变化,这反映了缺乏共识。

结论

即使组织病理学可能有助于找出死因,但并不总是进行。然而,组织学在确定死因方面总是有帮助的这一假设受到了挑战。

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本文引用的文献

1
Audit of necropsy reporting in East Anglia.东安格利亚地区尸检报告审计。
J Clin Pathol. 1997 Aug;50(8):691-4. doi: 10.1136/jcp.50.8.691.
2
The coroner's necropsy in sudden death: an under-used source of epidemiological information.验尸官对猝死病例的尸检:一个未得到充分利用的流行病学信息来源。
J Clin Pathol. 1996 Sep;49(9):737-40. doi: 10.1136/jcp.49.9.737.
3
Practice guidelines for necropsy: time for action.尸检实践指南:行动时刻
J Clin Pathol. 1996 Nov;49(11):867-8. doi: 10.1136/jcp.49.11.867.
4
Physicians' attitudes to the autopsy.医生对尸检的态度。
J R Coll Physicians Lond. 1993 Apr;27(2):116-8.
5
Practice guidelines for autopsy pathology. Autopsy performance. Autopsy Committee of the College of American Pathologists.
Arch Pathol Lab Med. 1994 Jan;118(1):19-25.
6
Can histopathologists diagnose bronchopneumonia?组织病理学家能诊断支气管肺炎吗?
J Clin Pathol. 1995 Feb;48(2):120-3. doi: 10.1136/jcp.48.2.120.
7
Necropsy as a research method in the age of molecular pathology.
Lancet. 1995 Oct 7;346(8980):945-8. doi: 10.1016/s0140-6736(95)91561-3.
8
Cost effectiveness of routine postmortem histology.常规尸检组织学的成本效益
J Clin Pathol. 1987 Apr;40(4):459-61. doi: 10.1136/jcp.40.4.459.