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令人兴奋的体验会使神经元兴奋性降低。

Exciting experiences make neurons less excitable.

机构信息

Neuroscience and Behavior Program and the Department of Psychological and Brain Sciences, University of Massachusetts Amherst, Amherst, United States.

出版信息

Elife. 2017 Jul 27;6:e29763. doi: 10.7554/eLife.29763.

DOI:10.7554/eLife.29763
PMID:28749341
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5531828/
Abstract

Neurons in the brain of a female mouse that respond to the scent of a given male become suppressed after mating.

摘要

在一只雌性老鼠的大脑中，对特定雄性气味有反应的神经元在交配后会被抑制。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c626/5531828/74bfa4e2c117/elife-29763-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c626/5531828/74bfa4e2c117/elife-29763-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c626/5531828/74bfa4e2c117/elife-29763-fig1.jpg

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本文引用的文献

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Neural mechanisms of social learning in the female mouse.雌性小鼠社会学习的神经机制
Elife. 2017 Jun 16;6:e25421. doi: 10.7554/eLife.25421.
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Neural control of maternal and paternal behaviors.神经控制母性行为和父性行为。
Science. 2014 Aug 15;345(6198):765-70. doi: 10.1126/science.1253291. Epub 2014 Aug 14.
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In vivo vomeronasal stimulation reveals sensory encoding of conspecific and allospecific cues by the mouse accessory olfactory bulb.体内犁鼻器刺激揭示了小鼠副嗅球对同种和异种线索的感觉编码。
Proc Natl Acad Sci U S A. 2010 Mar 16;107(11):5172-7. doi: 10.1073/pnas.0915147107. Epub 2010 Mar 1.
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The main and the accessory olfactory systems interact in the control of mate recognition and sexual behavior.主嗅觉系统和副嗅觉系统在配偶识别和性行为的控制中相互作用。
Behav Brain Res. 2009 Jun 25;200(2):268-76. doi: 10.1016/j.bbr.2009.01.020.
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Noradrenergic induction of odor-specific neural habituation and olfactory memories.去甲肾上腺素能诱导气味特异性神经习惯化和嗅觉记忆。
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Synaptic plasticity: multiple forms, functions, and mechanisms.突触可塑性：多种形式、功能及机制。
Neuropsychopharmacology. 2008 Jan;33(1):18-41. doi: 10.1038/sj.npp.1301559. Epub 2007 Aug 29.
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Lhx6 delineates a pathway mediating innate reproductive behaviors from the amygdala to the hypothalamus.Lhx6描绘了一条介导从杏仁核到下丘脑的先天性生殖行为的通路。
Neuron. 2005 May 19;46(4):647-60. doi: 10.1016/j.neuron.2005.04.011.
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Role of olfactory sense in pregnancy block by strange males.
Science. 1960 May 20;131(3412):1526. doi: 10.1126/science.131.3412.1526.
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Structure and function of the vomeronasal system: an update.犁鼻系统的结构与功能：最新进展
Prog Neurobiol. 2003 Jun;70(3):245-318. doi: 10.1016/s0301-0082(03)00103-5.
10
Single-unit analysis of postnatal olfactory learning: modified olfactory bulb output response patterns to learned attractive odors.产后嗅觉学习的单神经元分析：嗅球对习得的吸引性气味的输出反应模式改变
J Neurosci. 1987 Oct;7(10):3154-62. doi: 10.1523/JNEUROSCI.07-10-03154.1987.