Grey Jeremy A, Bernstein Kyle T, Sullivan Patrick S, Kidd Sarah E, Gift Thomas L, Hall Eric W, Hankin-Wei Abigail, Weinstock Hillard S, Rosenberg Eli S
*Department of Epidemiology, Emory University Rollins School of Public Health, Atlanta, GA; †Division of STD Prevention, Centers for Disease Control and Prevention, Atlanta, GA; and ‡Department of Emergency Medicine, Emory University School of Medicine, Atlanta, GA.
J Acquir Immune Defic Syndr. 2017 Nov 1;76(3):e65-e73. doi: 10.1097/QAI.0000000000001508.
Men who have sex with men (MSM) in the United States experience an approximately 100-fold greater rate of primary and secondary (P&S) syphilis diagnoses compared with men who have sex with women only. As in the general population, racial/ethnic disparities in P&S syphilis diagnosis rates may exist among MSM, but MSM-specific P&S syphilis rates by race/ethnicity are unavailable. We enhanced a published modeling approach to estimate area-level MSM populations by race/ethnicity and provide the first estimates of P&S syphilis among black and white non-Hispanic MSM.
We used data from the American Community Survey (ACS), published findings from the National Health and Nutrition Examination Survey (NHANES), and national syphilis surveillance data to estimate state-level rates of P&S syphilis diagnoses among MSM, overall and for black and white non-Hispanic MSM. We also used variability around ACS and NHANES estimates to calculate 95% confidence intervals for each rate.
Among 11,359 cases of P&S syphilis among MSM with known race/ethnicity in 2014, 72.5% were among white (40.3%) or black (32.2%) MSM. The national rate of P&S syphilis diagnosis was 168.4/100,000 for white MSM and 583.9/100,000 for black MSM. Regional rates for black MSM ranged from 602.0/100,000 (South) to 521.5/100,000 (Midwest) and were consistently higher than those for white MSM.
Although white MSM accounted for more P&S syphilis diagnoses than black MSM in 2014, when evaluating diagnoses based on rate per 100,000, black MSM had consistently and markedly higher rates than white MSM, with the highest impacted states located in the US South.
在美国,与男性发生性关系的男性(MSM)的一期和二期梅毒诊断率比只与女性发生性关系的男性高约100倍。与普通人群一样,MSM中可能存在一期和二期梅毒诊断率的种族/民族差异,但尚无按种族/民族划分的特定于MSM的一期和二期梅毒发病率数据。我们改进了一种已发表的建模方法,以按种族/民族估计地区层面的MSM人群,并提供了非西班牙裔黑人和白人MSM中一期和二期梅毒的首次估计数据。
我们使用了美国社区调查(ACS)的数据、国家健康和营养检查调查(NHANES)公布的结果以及国家梅毒监测数据,来估计MSM总体以及非西班牙裔黑人和白人MSM中一期和二期梅毒诊断的州级发病率。我们还利用ACS和NHANES估计值的变异性来计算各发病率的95%置信区间。
在2014年已知种族/民族的MSM的11359例一期和二期梅毒病例中,72.5%发生在白人(40.3%)或黑人(32.2%)MSM中。白人MSM的全国一期和二期梅毒诊断率为168.4/10万,黑人MSM为583.9/10万。黑人MSM的地区发病率从602.0/10万(南部)到521.5/10万(中西部)不等,且一直高于白人MSM。
尽管2014年白人MSM的一期和二期梅毒诊断病例比黑人MSM多,但按每10万人发病率评估诊断情况时,黑人MSM的发病率一直且显著高于白人MSM,受影响最严重的州位于美国南部。