Xu Lili, Qin Ying, Yang Juan, Han Wei, Lei Youju, Feng Huaxiang, Zhu Xiaoyun, Li Yanming, Yu Hongjie, Feng Luzhao, Shi Yan
Institute for Infectious Disease Control and Prevention, Qinghai provincial Center for Disease Control and Prevention, Qinghai, China.
Western China Field Epidemiology Training Program, Beijing, China.
PLoS One. 2017 Jul 27;12(7):e0181539. doi: 10.1371/journal.pone.0181539. eCollection 2017.
Influenza vaccination has been shown to be the most effective preventive measure to reduce influenza virus infection and its related morbidity and mortality. Young children aged 6-59 months are recommended as one of the priority groups for seasonal influenza vaccination in China. Our study was conducted to evaluate the level of influenza vaccination coverage during 2014-15 and 2015-16 influenza seasons among kindergarten children aged 2-7 years in Xining, a low-income city of north-western China, and to explore potential factors for noncompliance associated with influenza vaccination. The coverage rate of influenza vaccination was 12.2% (95 CI: 10.6-14.2%) in 2014-15 and 12.8% (95 CI: 11.1-14.7%) in 2015-16. The low coverage rate was found to be primarily associated with the lack of knowledge about influenza vaccine in children's parents. The most common reason for vaccine declination was the concern about adverse reactions of vaccine. Therefore tailored information should be provided by clinician and public health doctors for targeted groups through effective methods to improve public understanding of vaccination.
流感疫苗接种已被证明是减少流感病毒感染及其相关发病率和死亡率的最有效预防措施。在中国，6至59个月大的幼儿被推荐为季节性流感疫苗接种的优先群体之一。我们的研究旨在评估中国西北部低收入城市西宁2至7岁幼儿园儿童在2014 - 15年和2015 - 16年流感季节的流感疫苗接种覆盖率，并探讨与流感疫苗接种不依从相关的潜在因素。2014 - 15年流感疫苗接种覆盖率为12.2%（95%置信区间：10.6 - 14.2%），2015 - 16年为12.8%（95%置信区间：11.1 - 14.7%）。发现低覆盖率主要与儿童家长对流感疫苗缺乏了解有关。拒绝接种疫苗最常见的原因是担心疫苗的不良反应。因此，临床医生和公共卫生医生应通过有效方法为目标群体提供针对性信息，以提高公众对疫苗接种的认识。
