Zhang Weiwei, Chen Xi, Fan Mingwen, Mulder Jan, Frencken Jo E
Oral Health Prev Dent. 2017;15(4):307-314. doi: 10.3290/j.ohpd.a38743.
To test the hypotheses: 1) cumulative survival rates of fully and partially retained high-viscosity glass-ionomer (HVGIC) ART sealants with heat application and glass-carbomer sealants on occlusal and free-smooth surfaces are both higher than that of resin sealants; 2) cumulative survival rate of fully and partially retained high-viscosity glass-ionomer ART sealant with heat application on occlusal and free-smooth surfaces is higher than that of comparable ART sealants without heat application.
The block-randomised clinical trial covered 405 eight-year-old children. The HVGIC was Ketac Molar Easymix, the glass carbomer was GlassCarbomer and the resin sealant was Clinpro. Retention rates of sealants on occlusal and free-smooth surfaces using conventional and modified categorisation (fully and partially retained sealants vs those completely lost [at least one-third of surface re-exposed]) were the dependent variables. The Kaplan-Meier survival method was used.
The cumulative survival rate of completely and partially retained resin sealants on occlusal (81.2%) and free-smooth (81%) surfaces after 4 years was statistically significantly higher, and that of glass-carbomer sealants (10.8% and 21.1%, respectively) was statistically significantly lower than those of the other sealant groups. There was no statistically significant difference in survival rates of completely and partially retained high-viscosity glass-ionomer ART sealants with (56% for both surfaces) or without heat application (56%) on occlusal and free-smooth surfaces (55.7% and 59.1%, respectively).
Resin sealants had the highest and glass-carbomer sealants the lowest retention rate after 4 years. Application of heat to high-viscosity glass-ionomer ART sealants did not result in a significantly higher sealant retention rate. Use of the modified categorisation for determining sealant retention is advocated.
验证以下假设：1）在咬合面和游离光滑面，经加热处理的完全保留和部分保留的高粘度玻璃离子（HVGIC）非创伤性修复治疗（ART）封闭剂以及玻璃卡波姆封闭剂的累积生存率均高于树脂封闭剂；2）在咬合面和游离光滑面，经加热处理的完全保留和部分保留的高粘度玻璃离子ART封闭剂的累积生存率高于未加热处理的同类ART封闭剂。
这项整群随机临床试验纳入了405名8岁儿童。使用的HVGIC为Ketac Molar Easymix，玻璃卡波姆为GlassCarbomer，树脂封闭剂为Clinpro。采用传统分类法和改良分类法（完全保留和部分保留的封闭剂与完全脱落[至少三分之一表面重新暴露]的封闭剂）来确定封闭剂在咬合面和游离光滑面的保留率，将其作为因变量。采用Kaplan-Meier生存分析法。
4年后，树脂封闭剂在咬合面（81.2%）和游离光滑面（81%）完全保留和部分保留的累积生存率在统计学上显著更高，而玻璃卡波姆封闭剂在这两个表面的累积生存率（分别为10.8%和21.1%）在统计学上显著更低。在咬合面和游离光滑面，经加热处理（两个表面均为56%）和未加热处理（56%）的完全保留和部分保留的高粘度玻璃离子ART封闭剂的生存率（分别为55.7%和59.1%）在统计学上无显著差异。
4年后，树脂封闭剂的保留率最高，玻璃卡波姆封闭剂的保留率最低。对高粘度玻璃离子ART封闭剂进行加热处理并未显著提高封闭剂的保留率。提倡使用改良分类法来确定封闭剂的保留情况。
