Department of Chemistry, College of Chemistry and Chemical Engineering, Guizhou University, Guiyang, Guizhou province 550025, P. R. China.
Nanoscale. 2017 Aug 10;9(31):10998-11003. doi: 10.1039/c7nr03760k.
Preparation of Pt-based nanocatalysts with high catalytic activity and exploration of their novel applications have attracted significant interest in the nanoscale field. Herein, we report a facile synthesis of dendritic PtNi nanoalloys and their applications for electrochemical nonenzymatic dopamine biosensors. As a result of their unique structure, the dendritic PtNi nanoalloys show high electrocatalytic activity towards dopamine oxidation. Amperometric dopamine biosensors based on dendritic PtNi nanoalloy microelectrode exhibit a wide linear detection ranges from 0.5 μM to 250 μM with ultrahigh sensitivity, fast response, and excellent selectivity at a potential of 0.3 V in a 0.1 M phosphate buffered solution (pH = 7.2). The limit of detection on dendritic PtNi nanoalloy microelectrodes can decrease down to 10 nM, which is the least concentration of dopamine in serum samples with a value of sensitivity up to 4.6 μA mg cm. This study shows an effective approach for the development of dendritic PtNi nanoalloys as electrocatalysts for electrochemical nonenzymatic dopamine biosensors.
制备具有高催化活性的 Pt 基纳米催化剂，并探索其在纳米领域的新应用，引起了人们的极大兴趣。在此，我们报告了树枝状 PtNi 纳米合金的简便合成及其在电化学非酶多巴胺生物传感器中的应用。由于其独特的结构，树枝状 PtNi 纳米合金对多巴胺氧化具有高电催化活性。基于树枝状 PtNi 纳米合金微电极的安培型多巴胺生物传感器在 0.1 M 磷酸盐缓冲溶液（pH = 7.2）中，在 0.3 V 的电势下，具有从 0.5 μM 到 250 μM 的宽线性检测范围、超高灵敏度、快速响应和优异的选择性。在树枝状 PtNi 纳米合金微电极上的检测限可降低至 10 nM，这是血清样品中多巴胺的最低浓度，其灵敏度值高达 4.6 μA mg cm。该研究为开发作为电化学非酶多巴胺生物传感器的电催化剂的树枝状 PtNi 纳米合金提供了一种有效方法。
