Ostroski Cassandra J, Drobatz Kenneth J, Reineke Erica L
Department of Clinical Sciences, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA, 19104.
J Vet Emerg Crit Care (San Antonio). 2017 Sep;27(5):561-568. doi: 10.1111/vec.12631. Epub 2017 Jul 28.
To describe patient characteristics, treatment, and outcome in male cats with urethral obstruction (UO) and fluid overload (FO), and to determine risk factors for the development of FO.
Retrospective case-control study from 2002-2012.
Eleven client-owned cats with UO that developed respiratory distress secondary to suspected FO and 51 control cats with UO without FO.
None.
Medical records of cats with UO and FO were identified. FO was defined as the development of respiratory distress secondary to pleural effusion or pulmonary edema while receiving IV fluids. To identify risk factors for FO, variables for cats that developed FO were compared with variables from a randomly selected control group of unaffected UO cats during the same time period. Variables analyzed included patient signalment, previous medical history, serum biochemical data, respiratory rate, cardiac auscultation abnormalities, admission systolic blood pressure, intravenous fluid administration, thoracic imaging, treatment, duration and cost of hospitalization, and outcome. Echocardiogram identified heart disease in 5/6 cats with FO. Cost (2.9 times as much) and median duration of hospitalization (4.1 vs 1.8 days) were significantly greater in cats with FO. Cats with FO were more likely to have received a fluid bolus (odds ratio [OR]: 5.1; 95% confidence interval [CI]: 1.3, 20, P = 0.014), developed a heart murmur (OR: 4.5; 95% CI, 1.1-18, P = 0.028) or a gallop sound (OR: 75; 95% CI, 8.1-694, P < 0.0001).
FO is a possible complication of the treatment of UO. The administration of a fluid bolus on presentation, and the development of a heart murmur or gallop sound during treatment were the most clinically useful risk factors identified. The development of FO is associated with significant increases in both the cost and length of hospitalization, but was not associated with increased mortality.
描述患有尿道梗阻（UO）和液体超负荷（FO）的雄性猫的患者特征、治疗及预后，并确定发生FO的危险因素。
2002年至2012年的回顾性病例对照研究。
11只因疑似FO继发呼吸窘迫的客户拥有的患有UO的猫，以及51只没有FO的患有UO的对照猫。
无。
确定了患有UO和FO的猫的病历。FO被定义为在接受静脉输液时因胸腔积液或肺水肿继发呼吸窘迫。为了确定FO的危险因素，将发生FO的猫的变量与同一时期随机选择的未受影响的患有UO的对照组猫的变量进行比较。分析的变量包括患者特征、既往病史、血清生化数据、呼吸频率、心脏听诊异常、入院收缩压、静脉输液、胸部成像、治疗、住院时间和费用以及预后。超声心动图在5/6只患有FO的猫中发现了心脏病。患有FO的猫的费用（高2.9倍）和住院中位时间（4.1天对1.8天）显著更高。患有FO的猫更有可能接受了液体推注（优势比[OR]：5.1；95%置信区间[CI]：1.3，20，P = 0.014），出现心脏杂音（OR：4.5；95%CI，1.1 - 18，P = 0.028）或奔马律（OR：75；95%CI，8.1 - 694，P < 0.0001）。
FO是UO治疗的一种可能并发症。就诊时给予液体推注以及治疗期间出现心脏杂音或奔马律是确定的最具临床意义的危险因素。FO的发生与住院费用和住院时间的显著增加相关，但与死亡率增加无关。
