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高胰岛素血症/正常血糖及静脉输注脂肪乳剂疗法用于治疗猫严重氨氯地平中毒

Hyperinsulinemia/euglycemia and intravenous lipid emulsion therapy for the management of severe amlodipine toxicosis in a cat.

作者信息

Tinsman Audrey E, Bellis Tara J

机构信息

BluePearl Specialty + Emergency Pet Hospital New York NY USA.

Emergency & Critical Care Garden State Veterinary Services Iselin NJ USA.

出版信息

Clin Case Rep. 2021 Dec 7;9(12):e05175. doi: 10.1002/ccr3.5175. eCollection 2021 Dec.

DOI:10.1002/ccr3.5175
PMID:34934496
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8650752/
Abstract

Calcium-channel blockers (CCBs) are widely used in people and animals. Overdose can result in cardiovascular collapse and death. Hyperinsulinemia/euglycemia therapy (HIET) and intralipid therapy (ILT) are reported treatment options in people. This is the first report describing HIET and ILT as treatments for amlodipine toxicosis in a cat.

摘要

钙通道阻滞剂（CCBs）在人和动物中被广泛使用。过量使用可导致心血管衰竭和死亡。高胰岛素血症/正常血糖疗法（HIET）和脂肪乳剂疗法（ILT）在人类中是已报道的治疗选择。这是第一份将HIET和ILT描述为猫氨氯地平中毒治疗方法的报告。

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1
Hyperinsulinemia/euglycemia and intravenous lipid emulsion therapy for the management of severe amlodipine toxicosis in a cat.高胰岛素血症/正常血糖及静脉输注脂肪乳剂疗法用于治疗猫严重氨氯地平中毒
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2
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1
Fluid Overload.液体过载
Front Vet Sci. 2021 Jun 29;8:668688. doi: 10.3389/fvets.2021.668688. eCollection 2021.
2
Lipid emulsion attenuates extrinsic apoptosis induced by amlodipine toxicity in rat cardiomyoblasts.脂质乳剂可减轻氨氯地平毒性诱导的大鼠心肌细胞外源性细胞凋亡。
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Clin Toxicol (Phila). 2020 Nov;58(11):1042-1049. doi: 10.1080/15563650.2020.1725034. Epub 2020 Mar 2.
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A randomized controlled study comparing high-dose insulin to vasopressors or combination therapy in a porcine model of refractory propranolol-induced cardiogenic shock.一项比较高剂量胰岛素与血管加压药或联合治疗在难治性普萘洛尔诱导心源性休克猪模型中的随机对照研究。
Clin Toxicol (Phila). 2019 Nov;57(11):1073-1079. doi: 10.1080/15563650.2019.1580372. Epub 2019 Feb 26.
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Retrospective analysis of pleural effusion in cats.猫胸腔积液的回顾性分析。
J Feline Med Surg. 2019 Dec;21(12):1102-1110. doi: 10.1177/1098612X18816489. Epub 2018 Dec 17.
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An Update on Calcium Channel Blocker Toxicity in Dogs and Cats.犬猫钙通道阻滞剂中毒的最新情况
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A Fatal Case of Amlodipine Toxicity Following Iatrogenic Hypercalcemia.氨氯地平中毒致致命病例：医源性高钙血症。
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Treatment of Amlodipine Intoxication with Intravenous Lipid Emulsion Therapy: A Case Report and Review of the Literature.静脉用脂肪乳剂治疗氨氯地平中毒：病例报告及文献复习。
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Blood Pressure Measurements in 780 Apparently Healthy Cats.780只看似健康的猫的血压测量
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