Berthier A, Chamaret S, Fauchet R, Fonlupt J, Genetet N, Gueguen M, Pommereuil M, Ruffault A, Montagnier L
Lancet. 1986 Sep 13;2(8507):598-601. doi: 10.1016/s0140-6736(86)92427-x.
In a study of the transmissibility of human immunodeficiency virus (HIV) in haemophilic and non-haemophilic children living together in a boarding school in France, half of the haemophilic children had seroconverted by the end of a 3-year study period. By contrast none of the non-haemophilic children seroconverted. All children had had close casual contact, some of them for several years. Hepatitis B virus (HBV) markers detected in all polytransfused haemophiliacs were found in 4 of 20 control children in the school, whereas all healthy youngsters living with their families were HBV negative. This study adds support to the theory that transmissibility of HIV among casual contacts is low and that there is no reason to exclude HIV-antibody carriers from communities.
在法国一所寄宿学校中对共同生活的血友病和非血友病儿童进行的一项人类免疫缺陷病毒(HIV)传播性研究中,在为期3年的研究期结束时,一半的血友病儿童发生了血清转化。相比之下,非血友病儿童无一发生血清转化。所有儿童都有密切的日常接触,其中一些接触持续了数年。在所有接受多次输血的血友病患者中检测到的乙型肝炎病毒(HBV)标志物,在该校20名对照儿童中有4名检测到,而所有与家人一起生活的健康青少年HBV均为阴性。这项研究为以下理论提供了支持:HIV在日常接触者中的传播性较低,且没有理由将HIV抗体携带者排除在社区之外。