日本福冈血友病患者中人类免疫缺陷病毒（HIV）感染的患病率。

Prevalence of human immunodeficiency virus (HIV) infection among hemophiliacs in Fukuoka, Japan.

作者信息

Kashiwagi S, Hayashi J, Ikematsu H, Noguchi A, Ikeda K, Kishida K, Shirakawa M, Takenaka A, Mori R

机构信息

First Department of Internal Medicine, Faculty of Medicine, Kyushu University, Fukuoka.

出版信息

Microbiol Immunol. 1988;32(8):851-5. doi: 10.1111/j.1348-0421.1988.tb01446.x.

DOI:10.1111/j.1348-0421.1988.tb01446.x

PMID:3143898

Abstract

To determine when the hemophiliacs in Fukuoka prefecture, Japan, first became positive for antibodies, we tested human immunodeficiency virus (HIV) antibodies on serum samples obtained from 1976-1987 stored at -30 C. Fifteen out of 64 hemophilia A patients (23.4%), five out of 11 hemophilia B patients (45.5%), but none of 17 patients with von Willebrand's disease (0%) were positive for HIV antibodies. In this series, two with hemophilia A became positive for HIV antibodies for the first time in 1983, and in 1984 another four with hemophilia A and one with hemophilia B became positive.

摘要

为了确定日本福冈县的血友病患者首次出现抗体阳性的时间，我们对1976年至1987年期间保存在-30℃的血清样本进行了人类免疫缺陷病毒（HIV）抗体检测。64例甲型血友病患者中有15例（23.4%）、11例乙型血友病患者中有5例（45.5%）HIV抗体呈阳性，但17例血管性血友病患者中无一例（0%）HIV抗体呈阳性。在这组病例中，2例甲型血友病患者于1983年首次出现HIV抗体阳性，1984年又有4例甲型血友病患者和1例乙型血友病患者出现抗体阳性。