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A型肉毒杆菌毒素注射治疗继发性腋部臭汗症的疗效

Effectiveness of botulinum toxin A injection for the treatment of secondary axillary bromhidrosis.

作者信息

He Jinguang, Wang Tao, Dong Jiasheng

机构信息

Department of Plastic and Reconstructive Surgery, Shanghai 9th People's Hospital, Shanghai JiaoTong University School of Medicine, PR China.

Department of Plastic and Reconstructive Surgery, Shanghai 9th People's Hospital, Shanghai JiaoTong University School of Medicine, PR China.

出版信息

J Plast Reconstr Aesthet Surg. 2017 Nov;70(11):1641-1645. doi: 10.1016/j.bjps.2017.06.037. Epub 2017 Jul 8.

DOI:10.1016/j.bjps.2017.06.037
PMID:28754234
Abstract

Surgical removal of apocrine glands is a valid treatment option for axillary bromhidrosis. However, malodor may recur after the operation. The value of botulinum toxin A (BTX-A) injection in the treatment of secondary axillary bromhidrosis was investigated in the present study. From July of 2012 to May of 2016, 53 patients with secondary axillary bromhidrosis were enrolled in our clinic. Various BTX-A injection strategies were applied depending on different types of previous surgery. None of the patients reported adverse side effects after the procedure. The duration of efficacy ranged from 1 to 12 months, with the median value of 6 months. At the end of follow-up, 48 patients ranked the satisfaction with BTX-A treatment as "very good" or "good". For patients with secondary axillary bromhidrosis following various surgical modalities, the BTX-A treatment strategy we propose can achieve a lengthy duration of efficacy with a low risk of side effects and should be considered a good and reliable option.

摘要

手术切除顶泌汗腺是治疗腋窝臭汗症的一种有效方法。然而,术后异味可能会复发。本研究探讨了A型肉毒毒素(BTX-A)注射治疗继发性腋窝臭汗症的价值。2012年7月至2016年5月,53例继发性腋窝臭汗症患者入组本诊所。根据既往手术的不同类型采用了多种BTX-A注射策略。术后无一例患者报告有不良反应。疗效持续时间为1至12个月,中位数为6个月。随访结束时,48例患者对BTX-A治疗的满意度评为“非常好”或“好”。对于各种手术方式后出现继发性腋窝臭汗症的患者,我们提出的BTX-A治疗策略可实现较长的疗效持续时间,且副作用风险较低,应被视为一种良好且可靠的选择。

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