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Intracoronary delivery of recombinant TIMP-3 after myocardial infarction: effects on myocardial remodeling and function.
Am J Physiol Heart Circ Physiol. 2017 Oct 1;313(4):H690-H699. doi: 10.1152/ajpheart.00114.2017. Epub 2017 Jul 28.
2
Delivery of a matrix metalloproteinase-responsive hydrogel releasing TIMP-3 after myocardial infarction: effects on left ventricular remodeling.
Am J Physiol Heart Circ Physiol. 2018 Oct 1;315(4):H814-H825. doi: 10.1152/ajpheart.00076.2018. Epub 2018 Jul 6.
3
Targeted Injection of a Truncated Form of Tissue Inhibitor of Metalloproteinase 3 Alters Post-Myocardial Infarction Remodeling.
J Pharmacol Exp Ther. 2020 Nov;375(2):296-307. doi: 10.1124/jpet.120.000047. Epub 2020 Sep 21.
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Targeted overexpression of tissue inhibitor of matrix metalloproteinase-4 modifies post-myocardial infarction remodeling in mice.
Circ Res. 2014 Apr 25;114(9):1435-45. doi: 10.1161/CIRCRESAHA.114.303634. Epub 2014 Mar 17.
7
Myocardial overexpression of TIMP3 after myocardial infarction exerts beneficial effects by promoting angiogenesis and suppressing early proteolysis.
Am J Physiol Heart Circ Physiol. 2017 Aug 1;313(2):H224-H236. doi: 10.1152/ajpheart.00108.2017. Epub 2017 May 26.
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Accelerated LV remodeling after myocardial infarction in TIMP-1-deficient mice: effects of exogenous MMP inhibition.
Am J Physiol Heart Circ Physiol. 2005 Jan;288(1):H149-58. doi: 10.1152/ajpheart.00370.2004.

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1
Shear-Thinning Hydrogel for Delayed Delivery of a Small Molecule Metalloproteinase Inhibitor Attenuates Myocardial Infarction Remodeling.
JACC Basic Transl Sci. 2025 Apr;10(4):458-472. doi: 10.1016/j.jacbts.2024.11.009. Epub 2025 Jan 29.
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The TIMP protein family: diverse roles in pathophysiology.
Am J Physiol Cell Physiol. 2024 Mar 1;326(3):C917-C934. doi: 10.1152/ajpcell.00699.2023. Epub 2024 Jan 29.
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TIMP3 induces gene expression partly through PI3K and their association with vascularization and heart rate.
Front Cardiovasc Med. 2023 Mar 28;10:1130388. doi: 10.3389/fcvm.2023.1130388. eCollection 2023.
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Targeting Aggrecanases for Osteoarthritis Therapy: From Zinc Chelation to Exosite Inhibition.
J Med Chem. 2022 Oct 27;65(20):13505-13532. doi: 10.1021/acs.jmedchem.2c01177. Epub 2022 Oct 17.
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Modulation of Cardiac Fibrosis in and Beyond Cells.
Front Mol Biosci. 2021 Oct 27;8:750626. doi: 10.3389/fmolb.2021.750626. eCollection 2021.
9
Large Animal Models of Cell-Free Cardiac Regeneration.
Biomolecules. 2020 Sep 29;10(10):1392. doi: 10.3390/biom10101392.
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Biology of Tissue Inhibitor of Metalloproteinase 3 (TIMP3), and Its Therapeutic Implications in Cardiovascular Pathology.
Front Physiol. 2020 Jun 16;11:661. doi: 10.3389/fphys.2020.00661. eCollection 2020.

本文引用的文献

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Heart Disease and Stroke Statistics-2017 Update: A Report From the American Heart Association.
Circulation. 2017 Mar 7;135(10):e146-e603. doi: 10.1161/CIR.0000000000000485. Epub 2017 Jan 25.
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Advances in Uniportal Video-Assisted Thoracoscopic Surgery: Pushing the Envelope.
Thorac Surg Clin. 2016 May;26(2):187-201. doi: 10.1016/j.thorsurg.2015.12.007. Epub 2016 Feb 10.
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Matrix metalloproteinases as input and output signals for post-myocardial infarction remodeling.
J Mol Cell Cardiol. 2016 Feb;91:134-40. doi: 10.1016/j.yjmcc.2015.12.018. Epub 2015 Dec 23.
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Door to Balloon Time: Is There a Point That Is Too Short?
Prog Cardiovasc Dis. 2015 Nov-Dec;58(3):230-40. doi: 10.1016/j.pcad.2015.09.002. Epub 2015 Sep 15.
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Robotic CABG and Hybrid Approaches: The Current Landscape.
Prog Cardiovasc Dis. 2015 Nov-Dec;58(3):356-64. doi: 10.1016/j.pcad.2015.08.012. Epub 2015 Aug 28.
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Reperfusion strategies in acute coronary syndromes.
Circ Res. 2014 Jun 6;114(12):1918-28. doi: 10.1161/CIRCRESAHA.114.302744.
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Tissue inhibitor of metalloproteinase-1 and -3 improves cardiac function in an ischemic cardiomyopathy model rat.
Tissue Eng Part A. 2014 Nov;20(21-22):3073-84. doi: 10.1089/ten.TEA.2013.0763. Epub 2014 Jun 16.
8
Differential role of TIMP2 and TIMP3 in cardiac hypertrophy, fibrosis, and diastolic dysfunction.
Cardiovasc Res. 2014 Jul 15;103(2):268-80. doi: 10.1093/cvr/cvu072. Epub 2014 Apr 1.
10
Left ventricular remodeling in heart failure: current concepts in clinical significance and assessment.
JACC Cardiovasc Imaging. 2011 Jan;4(1):98-108. doi: 10.1016/j.jcmg.2010.10.008.

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