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急性脑卒中的机械取栓术-波兰五年的经验。

Mechanical thrombectomy in acute stroke - Five years of experience in Poland.

机构信息

Jagiellonian University, Poland.

The University Hospital in Cracow, Poland.

出版信息

Neurol Neurochir Pol. 2017 Sep-Oct;51(5):339-346. doi: 10.1016/j.pjnns.2017.05.004. Epub 2017 Jul 5.

DOI:10.1016/j.pjnns.2017.05.004
PMID:28756015
Abstract

OBJECTIVES

Mechanical thrombectomy (MT) is not reimbursed by the Polish public health system. We present a description of 5 years of experience with MT in acute stroke in Comprehensive Stroke Centers (CSCs) in Poland.

METHODS AND RESULTS

We retrospectively analyzed the results of a structured questionnaire from 23 out of 25 identified CSCs and 22 data sets that include 61 clinical, radiological and outcome measures.

RESULTS

Most of the CSCs (74%) were founded at University Hospitals and most (65.2%) work round the clock. In 78.3% of them, the working teams are composed of neurologists and neuro-radiologists. All CSCs perform CT and angio-CT before MT. In total 586 patients were subjected to MT and data from 531 of them were analyzed. Mean time laps from stroke onset to groin puncture was 250±99min. 90.3% of the studied patients had MT within 6h from stroke onset; 59.3% of them were treated with IV rt-PA prior to MT; 15.1% had IA rt-PA during MT and 4.7% - emergent stenting of a large vessel. M1 of MCA was occluded in 47.8% of cases. The Solitaire device was used in 53% of cases. Successful recanalization (TICI2b-TICI3) was achieved in 64.6% of cases and 53.4% of patients did not experience hemorrhagic transformation. Clinical improvement on discharge was noticed in 53.7% of cases, futile recanalization - in 30.7%, mRS of 0-2 - in 31.4% and mRS of 6 in 22% of cases.

CONCLUSION

Our results can help harmonize standards for MT in Poland according to international guidelines.

摘要

目的

机械取栓(MT)不在波兰公共卫生系统的报销范围内。我们展示了波兰综合卒中中心(CSC)在急性卒中中进行 MT 的 5 年经验描述。

方法

我们回顾性分析了从 25 个已识别的 CSC 中的 23 个和 22 个数据集的结构化问卷结果,这些数据集包含 61 项临床、放射学和结局测量指标。

结果

大多数 CSC(74%)位于大学医院,大多数(65.2%)实行 24 小时工作制。其中 78.3%的团队由神经科医生和神经放射科医生组成。所有 CSC 在 MT 前都进行 CT 和血管造影 CT。共有 586 名患者接受 MT,其中 531 名患者的数据进行了分析。从卒中发病到股动脉穿刺的平均时间间隔为 250±99 分钟。90.3%的研究患者在卒中发病后 6 小时内接受 MT;59.3%的患者在 MT 前接受 IV rt-PA;15.1%的患者在 MT 期间接受 IA rt-PA,4.7%的患者进行大血管紧急支架置入。MCA M1 闭塞的病例占 47.8%。Solitaire 装置的使用比例为 53%。64.6%的病例实现了成功再通(TICI2b-TICI3),53.4%的患者没有发生出血性转化。出院时临床改善的比例为 53.7%,无效再通的比例为 30.7%,mRS 为 0-2 的比例为 31.4%,mRS 为 6 的比例为 22%。

结论

我们的结果可以帮助根据国际指南协调波兰 MT 的标准。

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