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呼吸不规则与迟发性运动障碍。一项患病率研究。

Respiratory irregularity and tardive dyskinesia. A prevalence study.

作者信息

Yassa R, Lal S

出版信息

Acta Psychiatr Scand. 1986 May;73(5):506-10. doi: 10.1111/j.1600-0447.1986.tb02717.x.

DOI:10.1111/j.1600-0447.1986.tb02717.x
PMID:2875609
Abstract

In a survey of 351 chronically hospitalized adult psychiatric patients, clinical evidence of irregular respiration compatible with respiratory tardive dyskinesia was present in eight subjects (2.3%). In four, audible involuntary respiratory noises were present. All patients with respiratory irregularities had a facio-bucco-lingual dyskinesia and in four the dyskinesia also involved extremities and/or other regions of the body. The prevalence of respiratory irregularities amongst patients with tardive dyskinesia was eight out of 108 (7.4%); none of the patients without tardive dyskinesia had respiratory irregularities. The prevalence of respiratory irregularities was significantly greater in patients with an organic mental disorder (11.1%) compared with those without (1.3%) (P less than 0.005). None of the patients complained of their respiratory symptoms and none had been diagnosed as having a respiratory dyskinesia prior to the survey. In two patients the symptoms were severe, leading in one case to prominent gasping, dysphagia, severe choking when eating, and episodes of aspiration pneumonia. In a second patient the noisy respiration was interpreted as attention-seeking and intimidating behaviour which led to rejection by the staff. In the remaining six patients respiratory symptoms were relatively minor.

摘要

在一项对351名长期住院的成年精神科患者的调查中,8名受试者(2.3%)存在与呼吸性迟发性运动障碍相符的不规则呼吸的临床证据。其中4名患者有可闻及的非自主性呼吸噪音。所有呼吸不规则的患者均有面-颊-舌运动障碍,4名患者的运动障碍还累及肢体和/或身体的其他部位。迟发性运动障碍患者中呼吸不规则的患病率为108例中的8例(7.4%);无迟发性运动障碍的患者均无呼吸不规则。有器质性精神障碍的患者中呼吸不规则的患病率(11.1%)显著高于无器质性精神障碍的患者(1.3%)(P<0.005)。所有患者均未主诉呼吸症状,且在调查前均未被诊断为呼吸运动障碍。2名患者症状严重,其中1例导致明显的喘息、吞咽困难、进食时严重呛噎及吸入性肺炎发作。另1例患者呼吸嘈杂被认为是寻求关注和恐吓行为,导致被工作人员排斥。其余6名患者的呼吸症状相对较轻。

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