Majumdar S K
Acta Psychiatr Scand Suppl. 1986;329:69-72. doi: 10.1111/j.1600-0447.1986.tb10538.x.
The neuro-endocrine system is affected by chronic ethanol ingestion. Chlormethiazole is effective in the treatment of the ethanol withdrawal syndrome because of its tolerability, lack of hepatotoxicity, short plasma half-life, lack of any long-acting intermediate metabolites and lack of adverse effects on the neuro-endocrine system in alcoholics.
神经内分泌系统会受到长期摄入乙醇的影响。氯美噻唑因其耐受性良好、无肝毒性、血浆半衰期短、不存在任何长效中间代谢产物以及对酗酒者的神经内分泌系统无不良影响,故而对乙醇戒断综合征的治疗有效。