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一般地中海人群中心血管踝臂指数的差异取决于是否存在代谢心血管危险因素。

Differences in cardio-ankle vascular index in a general Mediterranean population depending on the presence or absence of metabolic cardiovascular risk factors.

机构信息

Institut Universitari d'Investigació en Atenció Primària Jordi Gol (IDIAP Jordi Gol), Catalunya, Spain; ISV Research Group, Research Unit in Primary Care, Primary Care Services, Girona. Institut Català de la Salut (ICS), Catalunya, Spain; Biomedical Research Institute, Girona (IdIBGi). ICS, Catalunya, Spain.

Institut Universitari d'Investigació en Atenció Primària Jordi Gol (IDIAP Jordi Gol), Catalunya, Spain; ISV Research Group, Research Unit in Primary Care, Primary Care Services, Girona. Institut Català de la Salut (ICS), Catalunya, Spain.

出版信息

Atherosclerosis. 2017 Sep;264:29-35. doi: 10.1016/j.atherosclerosis.2017.07.013. Epub 2017 Jul 13.

Abstract

BACKGROUND AND AIMS

The main aim of this study is to describe the differences in the cardio-ankle vascular index (CAVI) in individuals with metabolic cardiovascular risk factors or a previous history of vascular diseases (WCVRF) compared to healthy individuals (free of risk factors and previous history of vascular diseases; FCVRF) in a general Mediterranean population. The secondary aim is to describe the proportion of CAVI≥9 depending on the cardiovascular risk category in both CVRF groups by sex.

METHODS

The study is a descriptive analysis of 2613 participants randomly selected in the Girona province (Catalonia, Spain).

RESULTS

CAVI mean differences between sexes and age categories in both CVRF groups followed the same pattern, the FCVRF group (men 25.2%; women 14.4%) in turn had a lower prevalence of CAVI≥9 than the WCVRF group (men 57.9%; women 51.8%). The percentage of men and women with CAVI≥9 with low risk was 13.9% and 11.3% in the FCVRF group, and 31.8% and 42.0% in the WCVRF group; with moderate risk, it was 55.8% and 10.0% in the FCVRF group and 60.3% and 49.0% in the WCVRF group.

CONCLUSIONS

In both sexes, FCVRF groups had a lower prevalence of CAVI≥9 as well as lower mean CAVI scores, across all 10 year-age categories from 40 to 69 years, than WCVRF groups. Moreover, CAVI≥9 was frequent in individuals with low and moderate coronary risk in the WCVRF group but also in the FCVRF group. These results suggest that CAVI assessment to detect asymptomatic arteriosclerosis could be a useful tool to improve cardiovascular risk stratification.

摘要

背景和目的

本研究的主要目的是描述代谢性心血管危险因素或既往血管疾病史个体(WCVRF)与无危险因素和既往血管疾病史个体(FCVRF)之间心血管踝臂指数(CAVI)的差异在一般地中海人群中。次要目的是描述两个 CVRF 组中根据心血管风险类别,CAVI≥9 的比例。

方法

该研究是对加泰罗尼亚(西班牙)吉罗纳省随机选择的 2613 名参与者进行的描述性分析。

结果

两个 CVRF 组中性别和年龄组之间的 CAVI 平均差异遵循相同模式,FCVRF 组(男性 25.2%;女性 14.4%)的 CAVI≥9 患病率低于 WCVRF 组(男性 57.9%;女性 51.8%)。CAVI≥9 的低危男性和女性比例分别为 FCVRF 组的 13.9%和 11.3%,WCVRF 组的 31.8%和 42.0%;中危男性和女性比例分别为 FCVRF 组的 55.8%和 10.0%,WCVRF 组的 60.3%和 49.0%。

结论

在两性中,FCVRF 组在 40 至 69 岁的所有 10 年年龄组中,CAVI≥9 的患病率较低,CAVI 平均评分也较低,高于 WCVRF 组。此外,WCVRF 组中低危和中危冠心病患者以及 FCVRF 组中 CAVI≥9 较为常见。这些结果表明,CAVI 评估检测无症状动脉硬化可能是改善心血管风险分层的有用工具。

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