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职业性和准职业性石棉暴露导致的肺癌和间皮瘤的经济负担。

The economic burden of lung cancer and mesothelioma due to occupational and para-occupational asbestos exposure.

作者信息

Tompa Emile, Kalcevich Christina, McLeod Chris, Lebeau Martin, Song Chaojie, McLeod Kim, Kim Joanne, Demers Paul A

机构信息

Institute for Work and Health, Toronto, Ontario, Canada.

Department of Economics, McMaster University, Hamilton, Ontario, Canada.

出版信息

Occup Environ Med. 2017 Nov;74(11):816-822. doi: 10.1136/oemed-2016-104173. Epub 2017 Jul 29.

DOI:10.1136/oemed-2016-104173
PMID:28756416
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5740539/
Abstract

OBJECTIVES

To estimate the economic burden of lung cancer and mesothelioma due to occupational and para-occupational asbestos exposure in Canada.

METHODS

We estimate the lifetime cost of newly diagnosed lung cancer and mesothelioma cases associated with occupational and para-occupational asbestos exposure for calendar year 2011 based on the societal perspective. The key cost components considered are healthcare costs, productivity and output costs, and quality of life costs.

RESULTS

There were 427 cases of newly diagnosed mesothelioma cases and 1904 lung cancer cases attributable to asbestos exposure in 2011 for a total of 2331 cases. Our estimate of the economic burden is $C831 million in direct and indirect costs for newly identified cases of mesothelioma and lung cancer and $C1.5 billion in quality of life costs based on a value of $C100 000 per quality-adjusted life year. This amounts to $C356 429 and $C652 369 per case, respectively.

CONCLUSIONS

The economic burden of lung cancer and mesothelioma associated with occupational and para-occupational asbestos exposure is substantial. The estimate identified is for 2331 newly diagnosed, occupational and para-occupational exposure cases in 2011, so it is only a portion of the burden of existing cases in that year. Our findings provide important information for policy decision makers for priority setting, in particular the merits of banning the mining of asbestos and use of products containing asbestos in countries where they are still allowed and also the merits of asbestos removal in older buildings with asbestos insulation.

摘要

目的

评估加拿大因职业性和准职业性石棉暴露导致的肺癌和间皮瘤的经济负担。

方法

我们从社会角度估算了2011年与职业性和准职业性石棉暴露相关的新诊断肺癌和间皮瘤病例的终身成本。所考虑的关键成本组成部分包括医疗成本、生产力和产出成本以及生活质量成本。

结果

2011年,归因于石棉暴露的新诊断间皮瘤病例有427例,肺癌病例有1904例,共计2331例。我们估计,新确诊的间皮瘤和肺癌病例的直接和间接成本为8.31亿加元,基于每质量调整生命年10万加元的价值,生活质量成本为15亿加元。这分别相当于每例356429加元和652369加元。

结论

与职业性和准职业性石棉暴露相关的肺癌和间皮瘤的经济负担巨大。所确定的估计数是针对2011年2331例新诊断的职业性和准职业性暴露病例,因此这只是该年现有病例负担的一部分。我们的研究结果为政策决策者进行优先事项设定提供了重要信息,特别是在仍允许开采石棉和使用含石棉产品的国家禁止此类活动的好处,以及在有石棉隔热材料的旧建筑中清除石棉的好处。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2abc/5740539/e2cb58162dd2/oemed-2016-104173f02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2abc/5740539/d291e7e56b22/oemed-2016-104173f01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2abc/5740539/e2cb58162dd2/oemed-2016-104173f02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2abc/5740539/d291e7e56b22/oemed-2016-104173f01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2abc/5740539/e2cb58162dd2/oemed-2016-104173f02.jpg

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本文引用的文献

1
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2
Heart disease and stroke statistics--2015 update: a report from the American Heart Association.《2015年心脏病和中风统计数据更新:美国心脏协会报告》
Circulation. 2015 Jan 27;131(4):e29-322. doi: 10.1161/CIR.0000000000000152. Epub 2014 Dec 17.
3
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加拿大癌症患者劳动力市场收入的纵向评估。
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4
Social return on investment economic evaluation of supportive care for lung cancer patients in acute care settings in Australia.澳大利亚急性护理环境中支持性护理肺癌患者的社会投资回报经济评价。
BMC Health Serv Res. 2022 Nov 23;22(1):1399. doi: 10.1186/s12913-022-08800-x.
5
Counting the social, psychological, and economic costs of COVID-19 for cancer patients.计算 COVID-19 给癌症患者带来的社会、心理和经济成本。
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6
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7
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8
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5
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