Lopez Liurka V, Rodriguez Michael G, Siegal Gene P, Wei Shi
Department of Pathology, The University of Alabama at Birmingham, Birmingham, AL 35249, United States.
Department of Radiology, The University of Alabama at Birmingham, Birmingham, AL 35249, United States.
Pathol Res Pract. 2017 Nov;213(11):1445-1449. doi: 10.1016/j.prp.2017.07.001. Epub 2017 Jul 6.
Aneurysmal bone cyst (ABC) is an expansile cystic lesion that may affect any bone of the skeleton. Although exceedingly rare, lesions with histomorphologic characteristics of an ABC have reportedly originated within soft tissue. Extraskeletal ABC may mimic a variety of benign and malignant lesions and can be confused with other more common or rare giant cell-rich tumors of soft tissue, especially myositis ossificans. Clinical, radiological and histologic correlation is crucial in reaching the correct diagnosis. Cytogenetic and/or molecular genetic analysis is a useful adjunct in diagnosing these exquisitely rare lesions. Here we report a case of an ABC arising in an extraskeletal site and provide a comprehensive review of literature on this rare entity.
动脉瘤样骨囊肿(ABC)是一种可累及骨骼任何部位的膨胀性囊性病变。尽管极为罕见,但据报道具有ABC组织形态学特征的病变可起源于软组织。骨外ABC可模仿多种良性和恶性病变,并可能与其他更常见或罕见的富含巨细胞的软组织肿瘤混淆,尤其是骨化性肌炎。临床、放射学和组织学的相关性对于做出正确诊断至关重要。细胞遗传学和/或分子遗传学分析是诊断这些极其罕见病变的有用辅助手段。在此,我们报告一例发生于骨外部位的ABC病例,并对关于这一罕见实体的文献进行全面综述。