关于 OPT101 传感器在 ICU 临床近红外光谱仪中的应用的简要综述。

School of Microelectronics and Solid-state electronics, University of Electronic Science & Technology of China, Chengdu 610054, China.

Institute of Biomedical Engineering, Chinese Academy of Medical Science and Peking Union Medical College, Tianjin 300192, China.

Sensors (Basel). 2017 Jul 25;17(8):1701. doi: 10.3390/s17081701.

The optoelectronic sensor OPT101 have merits in advanced optoelectronic response characteristics at wavelength range for medical near-infrared spectroscopy and small-size chip design with build-in trans-impedance amplifier. Our lab is devoted to developing a series of portable near-infrared spectroscopy (NIRS) devices embedded with OPT101 for applications in intensive care unit clinics, based on NIRS principle. Here we review the characteristics and advantages of OPT101 relative to clinical NIRS instrumentation, and the most recent achievements, including early-diagnosis and therapeutic effect evaluation of thrombus, noninvasive monitoring of patients' shock severity, and fatigue evaluation. The future prospect on OPT101 improvements in noninvasive clinical applications is also discussed.

光电传感器 OPT101 在医学近红外光谱的波长范围内具有先进的光电响应特性，并且采用了小型芯片设计，内置跨阻放大器。我们的实验室致力于开发一系列基于近红外光谱（NIRS）原理、嵌入 OPT101 的便携式近红外光谱（NIRS）设备，用于重症监护病房临床。在这里，我们回顾了 OPT101 的特性和优势，相对于临床 NIRS 仪器，并介绍了最新的成果，包括血栓的早期诊断和治疗效果评估、对患者休克严重程度的无创监测以及疲劳评估。还讨论了 OPT101 在无创临床应用中的改进的未来前景。