Li Ting, Duan Meixue, Li Kai, Yu Guoqiang, Ruan Zhengshang
State Key Lab Elect Thin Film & Integrated Device and Department of Biomedical Engineering, University of Electronic Science & Technology of China, Chengdu 610054, China ; These authors contributed equally to this work ;
State Key Lab Elect Thin Film & Integrated Device and Department of Biomedical Engineering, University of Electronic Science & Technology of China, Chengdu 610054, China ; These authors contributed equally to this work.
Biomed Opt Express. 2015 Aug 19;6(9):3431-6. doi: 10.1364/BOE.6.003431. eCollection 2015 Sep 1.
Clinical monitoring of shock mainly depends on blood-oxygen-indices obtained from invasive blood sample tests. The central internal jugular central vein oxygenation level (ScvO2) has been considered as a gold standard indicator for shock prediction. We developed a noninvasive spatially-resolved near-infrared spectroscopy (SR-NIRS) to measure tissue blood oxygen saturation (StO2) surrounding the region of taking blood sample for the ScvO2 test in 25 patients with shock. StO2 values were found to be highly correlated (r = 0.84, p < 0.001) with ScvO2 levels and the concordance coefficient of 0.80 is high. The results suggest the potential of noninvasive SR-NIRS for bedside shock monitoring.
休克的临床监测主要依赖于有创血液样本检测所获得的血氧指标。中心颈内静脉血氧饱和度(ScvO2)一直被视为休克预测的金标准指标。我们开发了一种无创空间分辨近红外光谱技术(SR-NIRS),用于测量25例休克患者在进行ScvO2检测采血区域周围的组织血氧饱和度(StO2)。结果发现,StO2值与ScvO2水平高度相关(r = 0.84,p < 0.001),一致性系数为0.80,该系数较高。结果表明无创SR-NIRS用于床边休克监测具有潜力。