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男性下尿路症状/良性前列腺增生治疗的当前共识与争议

Current consensus and controversy on the treatment of male lower urinary tract symptoms/benign prostatic hyperplasia.

作者信息

Liao Chun-Hou, Kuo Hann-Chorng

机构信息

Department of Urology, Cardinal Tien Hospital and Fu-Jen Catholic University, New Taipei, Taiwan.

Department of Urology, Buddhist Tzu Chi General Hospital and Tzu Chi University, Hualien, Taiwan.

出版信息

Tzu Chi Med J. 2017 Jan-Mar;29(1):1-5. doi: 10.4103/tcmj.tcmj_2_17.

Abstract

Lower urinary tract symptoms (LUTS) are highly prevalent in men and increase with age. Because LUTS are common among elderly men, they are usually considered synonymous with benign prostatic hyperplasia (BPH). Drugs should be the first-line treatment for BPH and surgical intervention should be performed only when there are complications or LUTS refractory to medical treatment. In addition to medical treatment, several minimally invasive therapies, such as thermal therapy, prostatic lift, laser evaporation, or laser enucleation techniques have been developed. Recent investigations have also revealed that bladder dysfunction such as detrusor overactivity and detrusor underactivity may also contribute to male LUTS. In the treatment of LUTS suggestive of BPH (LUTS/BPH), the following questions should be considered: Is there an obstruction? Are we treating BPH or LUTS? Can management targeting BPH reduce LUTS? Should patients with LUTS be treated before bladder outlet obstruction is confirmed? What is the role of transurethral resection of the prostate (TURP) nowadays? Will new techniques provide better outcomes than TURP? This article discusses the current consensus and controversies in the treatment of LUTS/BPH.

摘要

下尿路症状(LUTS)在男性中极为普遍,且随年龄增长而增加。由于LUTS在老年男性中很常见,它们通常被视为与良性前列腺增生(BPH)同义。药物应作为BPH的一线治疗方法,仅在出现并发症或药物治疗难治的LUTS时才应进行手术干预。除药物治疗外,还开发了几种微创治疗方法,如热疗、前列腺悬吊术、激光汽化或激光剜除技术。最近的研究还表明,膀胱功能障碍,如逼尿肌过度活动和逼尿肌活动不足,也可能导致男性LUTS。在治疗提示BPH的LUTS(LUTS/BPH)时,应考虑以下问题:是否存在梗阻?我们是在治疗BPH还是LUTS?针对BPH的治疗能否减轻LUTS?在确认膀胱出口梗阻之前,是否应对LUTS患者进行治疗?如今经尿道前列腺切除术(TURP)的作用是什么?新技术是否会比TURP带来更好的治疗效果?本文讨论了LUTS/BPH治疗中的当前共识和争议。

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