Lupascu Cristian, Trofin Ana, Zabara Mihai, Vornicu Alexandra, Cadar Ramona, Vlad Nutu, Apopei Oana, Grigorean Valentin, Lupascu-Ursulescu Corina
Department of Surgery, University of Medicine and Pharmacy "Grigore T. Popa", Str. Universitatii nr. 16, 700115 Iasi, Romania.
Surgical Unit 2, "Sf. Spiridon" Hospital Iasi, Bd. Independentei nr. 1, Iasi, Romania.
Gastroenterol Res Pract. 2017;2017:2036951. doi: 10.1155/2017/2036951. Epub 2017 Jul 3.
During the past decades, the safety of pancreatoduodenectomy has improved, with low mortality and reduced morbidity, particularly in centers with extensive experience. Emergency pancreatoduodenectomy is an uncommon event, for treatment of pancreaticoduodenal trauma, bleeding, or perforation. We herein present a single center experience concerning nontrauma emergency pancreatoduodenectomy for pancreaticoduodenal bleeding.
From January 2007 to December 2015, from a population of 134 PD (70 males and 64 females, mean age 62.2, range 34-82), 5 patients (3.7%; 2 males and 3 females, mean age 64, range 57-70) underwent one-stage emergency pancreatoduodenectomy for uncontrollable nontrauma pancreaticoduodenal bleeding in our tertiary center.
All the 5 patients underwent a backwards Whipple with a morbidity of 60% and a mortality of 20% (1/5). The other 4 patients were recovered and discharged with a median postoperative length of stay of 17 days (range 14-23).
Emergency pancreatoduodenectomy is a definitive life-saving procedure allowing for a rapid control of bleeding when other less invasive approaches (transcatheter arterial embolization or interventional endoscopy) are exhausted, unavailable, or unsafe. It should be particularly considered in neoplastic disease and tailored by surgeons with a high level of experience in pancreatic surgery.
在过去几十年中,胰十二指肠切除术的安全性有所提高,死亡率降低,发病率减少,尤其是在经验丰富的中心。急诊胰十二指肠切除术并不常见,用于治疗胰十二指肠创伤、出血或穿孔。我们在此介绍单中心关于非创伤性急诊胰十二指肠切除术治疗胰十二指肠出血的经验。
2007年1月至2015年12月,在134例胰十二指肠切除术患者(70例男性和64例女性,平均年龄62.2岁,范围34 - 82岁)中,5例患者(3.7%;2例男性和3例女性,平均年龄64岁,范围57 - 70岁)在我们的三级中心因无法控制的非创伤性胰十二指肠出血接受了一期急诊胰十二指肠切除术。
所有5例患者均接受了逆行胰十二指肠切除术,发病率为60%,死亡率为20%(1/5)。其他4例患者康复出院,术后中位住院时间为17天(范围14 - 23天)。
急诊胰十二指肠切除术是一种明确的挽救生命的手术,当其他侵入性较小的方法(经导管动脉栓塞或介入性内镜检查)用尽、不可用或不安全时,可快速控制出血。在肿瘤性疾病中应特别考虑,由胰腺手术经验丰富的外科医生进行个体化操作。