Hulbert Justin C, Hirschstein Zall, Brontë Clarence A L, Broughton Eleanor
a Psychology Program , Bard College , Annandale-on-Hudson , NY , USA.
Memory. 2018 Mar;26(3):306-320. doi: 10.1080/09658211.2017.1354999. Epub 2017 Jul 31.
Forgetting can be either a source of great frustration or one of great relief, depending on whether the memories in question are relevant to one's immediate goals. Adopting an appropriate strategy or memory mode can help achieve these goals. But do efforts to control memory engender unintended side effects? Presently, we expand on a theoretical perspective of memory control, wherein efforts to suppress episodic encoding or retrieval result in the systemic downregulation of the hippocampal memory system. We review evidence from multiple methodologies, highlighting a non-invasive means of inducing amnesia that casts a shadow over memory for unrelated events. By establishing the causes and consequences of the amnesic side effects associated with memory control, we argue it may be possible to harness hippocampal dynamics to promote more adaptive memory performance in the lab, clinic, and broader context of daily life.
遗忘既可能是巨大挫折的根源，也可能是巨大解脱的来源，这取决于所涉及的记忆是否与一个人的当前目标相关。采用适当的策略或记忆模式有助于实现这些目标。但是，控制记忆的努力会产生意想不到的副作用吗？目前，我们扩展了一种记忆控制的理论视角，其中抑制情景编码或检索的努力会导致海马记忆系统的系统性下调。我们回顾了来自多种方法的证据，强调了一种诱导失忆的非侵入性方法，这种方法给无关事件的记忆蒙上了一层阴影。通过确定与记忆控制相关的失忆副作用的原因和后果，我们认为有可能利用海马动力学在实验室、临床以及更广泛的日常生活背景中促进更具适应性的记忆表现。
