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使用单纯血流导向支架置入术治疗破裂血泡样动脉瘤并考虑辅助性弹簧圈栓塞:单中心经验及文献综述

Treatment of ruptured blood blister aneurysms using primary flow-diverter stenting with considerations for adjunctive coiling: A single-centre experience and literature review.

作者信息

Yang Cunli, Vadasz Agnes, Szikora István

机构信息

Department of Neurointerventions, National Institute of Neurosciences, Budapest, Hungary.

出版信息

Interv Neuroradiol. 2017 Oct;23(5):465-476. doi: 10.1177/1591019917720805. Epub 2017 Jul 31.

Abstract

Objective The objective of this article is to conduct a single-centre evaluation and quick literature review of the effectiveness of primary flow-diverter (FD) treatment of ruptured blood blister aneurysms (BBAs), with additional relevance of adjunctive coiling. Methods Patients presenting with subarachnoid haemorrhage (SAH) due to ruptured BBAs and subsequently treated with FDs were retrospectively selected from June 2010 to January 2017. Treatment techniques, angiographic data on occlusion rates and procedural success as well as clinical outcomes using the modified Rankin Scale (mRS) were collated. Cross-reference of results were made with available literature. Results Thirteen patients harbouring 14 BBAs were recruited. Of the 14 aneurysms, five (35.7%) showed immediate complete occlusion after the procedure (four of these five patients had adjunctive coiling). All of the aneurysms showed complete occlusion by the six- to nine-month control diagnostic angiogram. No rebleed or retreatment was experienced. Twelve of 13 (92%) patients had an mRS score of 0-1 at the last clinical follow-up. From the pooled data of the literature review, eventual aneurysm occlusion was achieved in 48/56 patients, with five patients requiring further endovascular treatment. In the clinical follow-up period, an mRS of 0-2 was recorded for 83.3% (45/54) of patients. Conclusion Endovascular reconstruction of BBAs using FD treatment is an effective method with good final clinical outcomes. Adjunctive use of coiling achieves higher incidence of immediate complete occlusion of BBAs.

摘要

目的 本文旨在对原发性血流导向装置(FD)治疗破裂性血泡样动脉瘤(BBA)的有效性进行单中心评估并进行快速文献回顾,同时探讨辅助性弹簧圈栓塞的相关性。方法 回顾性选取2010年6月至2017年1月期间因破裂性BBA导致蛛网膜下腔出血(SAH)并随后接受FD治疗的患者。整理治疗技术、关于闭塞率和手术成功率的血管造影数据以及使用改良Rankin量表(mRS)评估的临床结局。将结果与现有文献进行交叉对照。结果 招募了13例患有14个BBA的患者。在这14个动脉瘤中,5个(35.7%)在手术后立即显示完全闭塞(这5例患者中有4例接受了辅助性弹簧圈栓塞)。所有动脉瘤在6至9个月的对照诊断血管造影中均显示完全闭塞。未发生再出血或再次治疗情况。13例患者中有12例(92%)在最后一次临床随访时mRS评分为0 - 1。从文献回顾的汇总数据来看,56例患者中有48例最终实现了动脉瘤闭塞,5例患者需要进一步的血管内治疗。在临床随访期间,83.3%(45/54)的患者mRS评分为0 - 2。结论 使用FD治疗对BBA进行血管内重建是一种有效的方法,最终临床结局良好。辅助性使用弹簧圈栓塞可使BBA立即完全闭塞的发生率更高。

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