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阿片类药物激动剂治疗中的创伤后应激障碍:综述。

Posttraumatic stress disorder in opioid agonist therapy: A review.

机构信息

VA HSR&D Houston Center of Excellence, Michael E. DeBakey VA Medical Center.

出版信息

Psychol Trauma. 2018 Nov;10(6):636-642. doi: 10.1037/tra0000312. Epub 2017 Jul 31.

Abstract

OBJECTIVE

Posttraumatic stress disorder (PTSD) and opioid use disorder (OUD) co-occur at high rates, and this co-occurrence is associated with a range of problems related to mental and physical health. OUD is commonly treated with opioid agonist therapies (OAT), which have been shown to be effective for reducing opiate use and related negative health consequences. Given the high comorbidity of PTSD and OUD, many individuals in OAT have PTSD and continue to experience symptoms of both disorders despite OAT treatment. In this review, the extant literature on PTSD among individuals in OAT is presented.

METHOD

Relevant studies (N = 26) were identified systematically through a search of PubMed and PsychInfo databases.

RESULTS

Literature regarding prevalence and clinical characteristics of patients with PTSD in OAT and treatment outcomes related to both OUD and PTSD is reviewed.

CONCLUSION

Clinical implications of the body of work and recommendations for future research are provided. (PsycINFO Database Record (c) 2018 APA, all rights reserved).

摘要

目的

创伤后应激障碍(PTSD)和阿片类药物使用障碍(OUD)的发生率都很高,这种共病与一系列与身心健康相关的问题有关。OUD 通常采用阿片类激动剂治疗(OAT),已证明该疗法可有效减少阿片类药物的使用和相关的健康不良后果。鉴于 PTSD 和 OUD 的高共病性,许多接受 OAT 的个体都患有 PTSD,并且尽管接受了 OAT 治疗,但仍继续经历两种疾病的症状。在这篇综述中,介绍了接受 OAT 的个体中 PTSD 的现有文献。

方法

通过对 PubMed 和 PsychInfo 数据库进行系统搜索,确定了相关研究(N = 26)。

结果

综述了关于 OAT 中 PTSD 患者的患病率和临床特征以及与 OUD 和 PTSD 相关的治疗结果的文献。

结论

提供了该研究领域的临床意义和对未来研究的建议。(APA,2018 版权所有)。

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