Song Wenhao, Zhou Dongsheng, Xu Weicheng, Zhang Guoming, Wang Chunhui, Qiu Daodi, Dong Jinlei
Department of Orthopedic Surgery, Shandong Provincial Hospital affiliated to Shandong University , Shandong, People's Republic of China.
Surg Infect (Larchmt). 2017 Aug/Sep;18(6):711-715. doi: 10.1089/sur.2017.083. Epub 2017 Jul 31.
Open pelvic fractures associated with rectal injuries are uncommon. They often cause serious pelvic infection, even death. This combination of injuries has been reviewed infrequently. Herein, we report factors associated with pelvic infection and death in a group of patients with open pelvic fractures and concurrent rectal injuries.
We retrospectively reviewed the records of patients with open pelvic fractures and rectal injuries who were treated at our institution from January 2010-April 2014. From the medical records, age, gender, Injury Severity Score (ISS), cause of fracture, associated injuries, classification of the fracture, degree of soft-tissue injury, Glasgow Coma Score (GCS), Revised Trauma Score (RTS), packed red blood cells (PRBCs) needed, presence/absence of shock, early colostomy (yes or no), drainage (yes or no), and rectal washout (yes or no) were extracted. Univariable and multivariable analysis were performed to determine the association between risk factors and pelvic infection or death.
Twenty patients were identified. Pelvic infection occurred in 50% (n = 10) of the patients. Four patients suffered septicemia, and three patients died of multiple organ dysfunction. The mortality rate thus was 15%. According to the univariable analysis, the patients in whom pelvic infection developed had shock, RTS ≤8, GCS ≤8, blood transfusion ≥10 units in the first 24 h, no colostomy, or Gustilo grade III soft-tissue injury. According to the multivariable analysis, shock and absence of colostomy were independently associated with pelvic infection. By univariable analysis, the only factor associated with death was RTS ≤8.
The incidence of pelvic infection was lower in patients having early colostomy (p < 0.05). Patients with shock had a higher risk of pelvic infection, and we recommend aggressive measures to treat these patients. According to our results, RTS ≤8 could be a predictor of poor outcomes in patients with open pelvic fracture and concurrent rectal injury. Open reduction and internal fixation after extensive debridement is recommended in patients with unstable pelvic fractures.
伴有直肠损伤的开放性骨盆骨折并不常见。它们常导致严重的盆腔感染,甚至死亡。对这种合并损伤的研究并不多。在此,我们报告一组开放性骨盆骨折并发直肠损伤患者中与盆腔感染和死亡相关的因素。
我们回顾性分析了2010年1月至2014年4月在我院接受治疗的开放性骨盆骨折并直肠损伤患者的记录。从病历中提取年龄、性别、损伤严重程度评分(ISS)、骨折原因、合并损伤、骨折分类、软组织损伤程度、格拉斯哥昏迷评分(GCS)、改良创伤评分(RTS)、所需浓缩红细胞(PRBC)数量、是否存在休克、是否早期行结肠造口术(是或否)、是否引流(是或否)以及是否进行直肠冲洗(是或否)。进行单因素和多因素分析以确定危险因素与盆腔感染或死亡之间的关联。
共确定了20例患者。50%(n = 10)的患者发生盆腔感染。4例患者发生败血症,3例患者死于多器官功能障碍。因此死亡率为15%。根据单因素分析,发生盆腔感染的患者存在休克、RTS≤8、GCS≤8、在最初24小时内输血≥10单位、未行结肠造口术或存在 Gustilo Ⅲ级软组织损伤。根据多因素分析,休克和未行结肠造口术与盆腔感染独立相关。通过单因素分析,与死亡相关的唯一因素是RTS≤8。
早期行结肠造口术的患者盆腔感染发生率较低(p < 0.05)。休克患者发生盆腔感染的风险较高,我们建议对这些患者采取积极的治疗措施。根据我们的结果,RTS≤8可能是开放性骨盆骨折并发直肠损伤患者预后不良的一个预测指标。对于不稳定骨盆骨折患者,建议在广泛清创后进行切开复位内固定。