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2010 - 2013年利比里亚蒙罗维亚一家狂犬病暴露转诊诊所收治的犬咬伤受害者的时间序列分析及死亡率模型

Time series analysis and mortality model of dog bite victims presented for treatment at a referral clinic for rabies exposure in Monrovia, Liberia, 2010-2013.

作者信息

Olarinmoye Ayodeji O, Ojo Johnson F, Fasunla Ayotunde J, Ishola Olayinka O, Dakinah Fahnboah G, Mulbah Charles K, Al-Hezaimi Khalid, Olugasa Babasola O

机构信息

Department of Agriculture and Industrial Technology (Animal Science Unit), Faculty of Science and Technology, Babcock University, Ilisan-Remo, Ogun State, Nigeria; Centre for Control and Prevention of Zoonoses, University of Ibadan, Ibadan, Nigeria; Engineer Abdullah Bugshan Research Chair for Growth Factors and Bone Regeneration, King Saud University, Saudi Arabia.

Centre for Control and Prevention of Zoonoses, University of Ibadan, Ibadan, Nigeria; Department of Statistics, Faculty of Science, University of Ibadan, Ibadan, Nigeria.

出版信息

Spat Spatiotemporal Epidemiol. 2017 Aug;22:1-13. doi: 10.1016/j.sste.2017.04.003. Epub 2017 May 25.

Abstract

We developed time trend model, determined treatment outcome and estimated annual human deaths among dog bite victims (DBVs) from 2010 to 2013 in Monrovia, Liberia. Data obtained from clinic records included victim's age, gender and site of bite marks, site name of residence of rabies-exposed patients, promptness of care sought, initial treatment and post-exposure-prophylaxis (PEP) compliance. We computed DBV time-trend plot, seasonal index and year 2014 case forecast. Associated annual human death (AHD) was estimated using a standardized decision tree model. Of the 775 DBVs enlisted, care seeking time was within 24h of injury in 328 (42.32%) DBVs. Victim's residential location, site of bite mark, and time dependent variables were significantly associated with treatment outcome (p< 0.05). The equation X^=28.278-0.365t models the trend of DBVs. The high (n=705, 90.97%) defaulted PEP and average 155 AHD from rabies implied urgent need for policy formulation on national programme for rabies prevention in Liberia.

摘要

我们建立了时间趋势模型,确定了治疗结果,并估计了2010年至2013年利比里亚蒙罗维亚犬咬伤受害者(DBV)的年度死亡人数。从诊所记录中获得的数据包括受害者的年龄、性别、咬痕部位、狂犬病暴露患者的居住地点名称、寻求治疗的及时性、初始治疗和暴露后预防(PEP)的依从性。我们计算了DBV时间趋势图、季节性指数和2014年病例预测。使用标准化决策树模型估计相关的年度人类死亡(AHD)。在登记的775名DBV中,328名(42.32%)DBV在受伤后24小时内寻求治疗。受害者的居住地点、咬痕部位和时间相关变量与治疗结果显著相关(p<0.05)。方程X^=28.278 - 0.365t模拟了DBV的趋势。大量(n = 705,90.97%)的人未进行PEP以及狂犬病平均每年导致155人死亡,这意味着利比里亚迫切需要制定关于国家狂犬病预防计划的政策。

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