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埃塞俄比亚狂犬病暴露后就医行为的决定因素。

Determinants of health seeking behaviour following rabies exposure in Ethiopia.

作者信息

Beyene T J, Mourits M C M, Revie C W, Hogeveen H

机构信息

Business Economics Group, Wageningen University, Wageningen, The Netherlands.

College of Veterinary Medicine and Agriculture, Addis Ababa University, Addis Ababa, Ethiopia.

出版信息

Zoonoses Public Health. 2018 Jun;65(4):443-453. doi: 10.1111/zph.12458. Epub 2018 Mar 10.

Abstract

The objective of this study was to identify factors that determine medical treatment seeking behaviour following potential rabies exposure after being bitten by a suspected dog and the likelihood of compliance to receive sufficient doses of post-exposure prophylaxis after the visit to a health centre visit. A detailed survey based on case investigation was conducted on suspected rabid dog bite cases in three areas of Ethiopia. Two multivariable logistic regression models were created with a set of putative variables to explain treatment seeking and compliance outcomes. Based on the registered bite cases at each health centre and the set of unregistered bite cases derived by contact tracing, 655 bite victim cases were identified to have occurred between September 2013 and August 2014. Of these evaluated bite incidences, 465 cases were considered to have been caused by a potentially rabid dog. About 77% of these suspected rabid dog bite victims visited a health centre, while 57% received sufficient doses of PEP. The overall likelihood of seeking medical services following rabies exposure was higher for people bitten by dogs of unknown ownership, where the bite was severe, being bitten on the leg, spend of more than 100 USD per month and where the victim lived close to the nearest health centre, while the likelihood of receiving sufficient doses of PEP was sensitive to monthly spending and distance to health centre. However, the evaluated factors did only explain a part of the variation among the three districts. The district in which victims lived appeared to have a relevant influence on the likelihood of seeking medical treatment but did not improve the prediction on the likelihood of treatment compliance. Given the insights obtained from this study, improvements in the rural districts with regard to accessibility of post-exposure prophylaxis delivering health centres in shorter distance could improve health seeking behaviour. In addition, in rural districts, majority of exposed persons who seek medical treatment tend to comply with treatment regimen, indicating that the promotion of medical treatment through awareness creation campaigns could be beneficial.

摘要

本研究的目的是确定在被疑似患有狂犬病的狗咬伤后,决定寻求医疗救治行为的因素,以及在前往健康中心就诊后接受足够剂量暴露后预防治疗的可能性。在埃塞俄比亚的三个地区,针对疑似狂犬病狗咬伤病例开展了基于病例调查的详细调查。利用一组假定变量创建了两个多变量逻辑回归模型,以解释寻求治疗和依从性结果。根据每个健康中心登记的咬伤病例以及通过接触追踪得出的未登记咬伤病例集,确定在2013年9月至2014年8月期间发生了655起咬伤受害者病例。在这些评估的咬伤事件中,465例被认为是由可能患有狂犬病的狗造成的。这些疑似狂犬病狗咬伤受害者中约77%前往了健康中心就诊,而57%接受了足够剂量的暴露后预防治疗。被不明犬主的狗咬伤、咬伤严重、腿部被咬、每月花费超过100美元以及受害者居住在离最近健康中心较近的地方的人,在狂犬病暴露后寻求医疗服务的总体可能性更高,而接受足够剂量暴露后预防治疗的可能性对每月花费和到健康中心的距离较为敏感。然而,所评估的因素仅解释了三个地区之间差异的一部分。受害者居住的地区似乎对寻求医疗治疗的可能性有显著影响,但并未改善对治疗依从性可能性的预测。鉴于从本研究中获得的见解,改善农村地区暴露后预防治疗健康中心的可及性,使其距离更近,可能会改善就医行为。此外,在农村地区,大多数寻求医疗治疗的暴露者往往会遵守治疗方案,这表明通过开展提高认识运动来促进医疗治疗可能会有益。

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