Rafik H, El Amrani M, El Kabbaj D
Department of Nephrology, Mohammed V Military Hospital, Faculty of Medicine and Pharmacy University Mohammed V-Souissi, Rabat, Morocco.
Indian J Nephrol. 2017 Jul-Aug;27(4):319-320. doi: 10.4103/0971-4065.202838.
Type 1 membranoproliferative glomerulonephritis (MPGN) is an uncommon manifestation of human immunodeficiency virus (HIV)-associated renal disease in patients coinfected with hepatitis C virus. We report a case of MPGN characterized by nephrotic syndrome associated with HIV without hepatitis C coinfection. The patient had a favorable response to highly active antiretroviral therapy and angiotensin-converting enzyme inhibitors. Recognition of the MPGN lesion in HIV infection devoid of hepatitis C coinfection must be considered.
1型膜增生性肾小球肾炎（MPGN）是丙型肝炎病毒合并感染的人类免疫缺陷病毒（HIV）相关肾病的一种罕见表现。我们报告了1例以肾病综合征为特征的MPGN病例，该患者感染了HIV但未合并丙型肝炎。患者对高效抗逆转录病毒治疗和血管紧张素转换酶抑制剂反应良好。必须考虑在未合并丙型肝炎感染的HIV感染中识别MPGN病变。
