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双侧腮腺肿大作为儿童急性淋巴细胞白血病的首发表现:一例病例报告及文献复习

Bilateral parotidomegaly as an initial manifestation of acute lymphoblastic leukemia in a child: A case report and review of literature.

作者信息

Sneha Latha Magatha, Subbiah Kaarthikeyani Sankaravadivelu, Scott Julius Xavier, Rajendiran Aruna

机构信息

Department of Pediatrics, Division of Pediatric Hemato Oncology, Sri Ramachandra University, Chennai, Tamil Nadu, India.

Department of Pediatrics, Sri Ramachandra University, Chennai, Tamil Nadu, India.

出版信息

Natl J Maxillofac Surg. 2017 Jan-Jun;8(1):55-57. doi: 10.4103/njms.NJMS_78_15.

DOI:10.4103/njms.NJMS_78_15
PMID:28761277
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5512410/
Abstract

The more common causes of parotid enlargement in children are infections and inflammatory conditions. Primary neoplasms of the parotid glands are rare in pediatric age group; however, secondary malignancies have been reported in survivors of childhood leukemia. The parotid glands have been the sites of relapses in acute lymphoblastic leukemia (ALL) and acute myeloid leukemia. However, bilateral parotid involvement as an initial presentation of ALL is rarely reported. We present a case of an 8-year-old boy who presented with bilateral parotid enlargement as an initial manifestation of ALL. General physicians should be aware of this extramedullary presentation of acute leukemia when they see a child presenting with organomegaly or abnormal blood counts.

摘要

儿童腮腺肿大更常见的原因是感染和炎症性疾病。腮腺原发性肿瘤在儿童年龄组中很少见;然而,儿童白血病幸存者中曾有继发性恶性肿瘤的报道。腮腺一直是急性淋巴细胞白血病(ALL)和急性髓细胞白血病复发的部位。然而,双侧腮腺受累作为ALL的初始表现很少被报道。我们报告一例8岁男孩,以双侧腮腺肿大作为ALL的初始表现。普通内科医生在见到有器官肿大或血常规异常的儿童时,应意识到急性白血病的这种髓外表现。

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引用本文的文献

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2
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3
Prolonged lumbosacral pain as the initial presentation in acute lymphoblastic leukemia in an adult: A case report.成人急性淋巴细胞白血病以长期腰骶部疼痛为首发表现:一例报告。
Medicine (Baltimore). 2019 Jun;98(24):e15912. doi: 10.1097/MD.0000000000015912.

本文引用的文献

1
An unusual presentation of pediatric acute lymphoblastic leukemia with parotid gland involvement and dactylitis.
Turk J Haematol. 2010 Jun 5;27(2):117-9. doi: 10.5152/tjh.2010.10.
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Bilateral parotid gland enlargement and palpable nephromegaly in infant acute lymphoblastic leukemia: case report and review of the literature.婴儿急性淋巴细胞白血病中的双侧腮腺肿大及可触及的肾肿大:病例报告及文献复习
J Pediatr Hematol Oncol. 2014 Apr;36(3):246-8. doi: 10.1097/MPH.0000000000000076.
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