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通过阻抗心动描记法测量心血管药物对健康受试者的作用。

Measurement of the effect of cardiovascular drugs by impedance cardiography in healthy subjects.

作者信息

Lücker P W, Venitz J, Adolph S, Hey B

出版信息

Methods Find Exp Clin Pharmacol. 1986 Jul;8(7):443-8.

PMID:2876133
Abstract

Impedance cardiography is a non-invasive electrical method designed to measure cardiac function on a beat-to-beat basis. Impedance changes within a constant high frequency AC-current field are detected by two thoracic electrodes. The potential changes within these two inner electrodes reflect impedance changes due to underlying pulsatile volume displacements. The relevance of the method was shown in investigations with a beta 1,beta 2-mimetic drug, a beta-blocker, an alpha-agonist, an alpha-blocker and a diuretic drug.

摘要

阻抗心动图是一种非侵入性的电学方法,旨在逐搏测量心脏功能。两个胸部电极检测恒定高频交流电流场内的阻抗变化。这两个内部电极内的电位变化反映了由于潜在的搏动性容量位移引起的阻抗变化。该方法的相关性在使用β1、β2拟似药物、β受体阻滞剂、α激动剂、α受体阻滞剂和利尿剂的研究中得到了证实。

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Measurement of the effect of cardiovascular drugs by impedance cardiography in healthy subjects.通过阻抗心动描记法测量心血管药物对健康受试者的作用。
Methods Find Exp Clin Pharmacol. 1986 Jul;8(7):443-8.
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