Lin Chunqing, Cao Xiaobin, Li Li
Semel Institute for Neuroscience and Human Behavior, University of California at Los Angeles, Los Angeles, California, U.S.A.
National Center for AIDS Prevention and Control, Chinese Center for Disease Control and Prevention, Beijing, China.
Int J Ment Health Addict. 2017 Aug;15(4):801-811. doi: 10.1007/s11469-017-9758-7. Epub 2017 Apr 21.
A proportion of methadone maintenance therapy (MMT) clients in China shifted their substance use habit from opiate to psychoactive substances. The objective of this study was to examine the pattern and associated factors of psychoactive substance use among MMT clients. The study was conducted among 2,448 clients from 68 MMT clinics of China. The type and frequency of psychoactive substance use were self-reported. About 38.1% (N=933) of the participants reported psychoactive substance use in lifetime, and 6.5% (N=158) in the previous 30 days. The most commonly used psychoactive substances were sedative/hypnotic/antidiarrheal agent and amphetamine. Psychoactive substance use in the past 30 days was correlated with younger age, recent heroin use, having psychoactive substance using friend(s), and depressive symptoms. The finding suggested that urinalysis of psychoactive substances should be routinely administered in the MMT clinics. Young clients, concurrent heroin users, and clients with depressive symptoms deserve more screening and intervention efforts.
中国部分美沙酮维持治疗（MMT）患者将其物质使用习惯从阿片类药物转向了精神活性物质。本研究的目的是调查MMT患者中精神活性物质使用的模式及相关因素。该研究在中国68家MMT诊所的2448名患者中开展。精神活性物质使用的类型和频率通过自我报告获取。约38.1%（N = 933）的参与者报告有过精神活性物质使用经历，6.5%（N = 158）在过去30天内有过使用。最常使用的精神活性物质是镇静/催眠/止泻剂和苯丙胺。过去30天内的精神活性物质使用与年龄较小、近期使用海洛因、有使用精神活性物质的朋友以及抑郁症状相关。该研究结果表明，MMT诊所应常规开展精神活性物质的尿液检测。年轻患者、同时使用海洛因的患者以及有抑郁症状的患者应接受更多的筛查和干预措施。
