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艾滋病疫情变迁及 HIV 检测假阳性相关因素:2013-2018 年中国西安的回顾性研究。

Shift in HIV/AIDS Epidemic and Factors Associated with False Positives for HIV Testing: A Retrospective Study from 2013 to 2018 in Xi'an, China.

机构信息

The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi Province, China.

出版信息

Curr HIV Res. 2020;18(3):219-226. doi: 10.2174/1570162X18666200415123607.

DOI:10.2174/1570162X18666200415123607
PMID:32294041
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7475938/
Abstract

BACKGROUND

In China, although quite a few bold programmes have been made for HIV/AIDS, the epidemic has still shown an increasing trend.

OBJECTIVES

The study was aimed to investigate the characteristics of new HIV/AIDS and the major factors of false positives (FP) for HIV testing.

METHODS

A retrospective review was performed in a teaching hospital in Xi'an between 2013 and 2018. The overall characteristics and trends of new HIV/AIDS were described. Moreover, the major factors of FP were determined by the Pareto analysis.

RESULTS

A total of 469 new HIV/AIDS were diagnosed, with an increasing prevalence of the new HIV/AIDS from 0.0626% (41/65503) in 2013 to 0.0827% (115/139046) in 2018. Of them, the majority occurred in the males (88.50%), people aged 21-50 years (76.97%), migrants (60.98%), and sexual contact route (88.70%). There was a rapid increase in the annual number of new HIV/AIDS and increasing trends in groups of young individuals, students, and homosexual mode; however, a downward trend in the percentage of injecting drug use was also observed. Over 50 years old and patients from oncology, obstetrics, hepatobiliary surgery, nephrology, cardiology, and infectious disease constituted the major factors of FP.

CONCLUSION

The HIV/AIDS epidemic in Xi'an is still evolving, therefore, effective strategies, appropriate education and scaling up HIV testing should be developed. In addition, old adults and specific departments were associated with FP.

摘要

背景

在中国,尽管已经制定了相当多的艾滋病防治计划,但艾滋病疫情仍呈上升趋势。

目的

本研究旨在调查新发现的艾滋病病毒/艾滋病(HIV/AIDS)患者的特征以及 HIV 检测假阳性(FP)的主要因素。

方法

回顾性分析了 2013 年至 2018 年期间西安某教学医院的 HIV/AIDS 新发病例。描述了新发现的 HIV/AIDS 的总体特征和趋势。此外,通过帕累托分析确定了 FP 的主要因素。

结果

共诊断出 469 例新的 HIV/AIDS 患者,HIV/AIDS 的发病率从 2013 年的 0.0626%(41/65503)上升到 2018 年的 0.0827%(115/139046)。其中,男性(88.50%)、21-50 岁人群(76.97%)、流动人口(60.98%)和性接触途径(88.70%)占大多数。新发现的 HIV/AIDS 患者人数呈快速增长趋势,青年人群、学生和同性恋者的比例呈上升趋势,而注射吸毒的比例呈下降趋势。50 岁以上人群和来自肿瘤科、妇产科、肝胆外科、肾病科、心内科和传染病科的患者是 FP 的主要因素。

结论

西安市的艾滋病疫情仍在演变,因此应制定有效的防控策略、开展适当的教育和扩大 HIV 检测。此外,老年人群和特定科室与 FP 相关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dc45/7475938/188bd78bca6e/CHIVR-18-219_F2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dc45/7475938/7b4f6817888f/CHIVR-18-219_F1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dc45/7475938/1b06b5eb3aab/CHIVR-18-219_F3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dc45/7475938/f4820a4a26ef/CHIVR-18-219_F4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dc45/7475938/188bd78bca6e/CHIVR-18-219_F2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dc45/7475938/7b4f6817888f/CHIVR-18-219_F1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dc45/7475938/1b06b5eb3aab/CHIVR-18-219_F3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dc45/7475938/f4820a4a26ef/CHIVR-18-219_F4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dc45/7475938/188bd78bca6e/CHIVR-18-219_F2.jpg

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Changing epidemiological patterns of HIV and AIDS in China in the post-SARS era identified by the nationwide surveillance system.中国在 SARS 后时代通过全国性监测系统确定的 HIV 和艾滋病的流行模式变化。
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