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[一名扩张型心肌病合并自动植入式除颤器(AID)患者的严重室性心律失常]

[Severe ventricular arrhythmias in a patient with dilated cardiomyopathy and automated implantable defibrillator (AID)].

作者信息

Ikama Stéphane Méo, Makani Jospin, Ellenga-Mbolla Bertrand, Ondze-Kafata Louis Igor, Gombet Thierry Raoul, Kimbally-Kaky Gisèle

机构信息

Service de Cardiologie, CHU de Brazzaville, Congo.

Service des Urgences, CHU de Brazzaville, Congo.

出版信息

Pan Afr Med J. 2017 May 11;27:31. doi: 10.11604/pamj.2017.27.31.12274. eCollection 2017.

Abstract

Severe ventricular arrhythmias are frequent during heart failure; they are a life-threatening condition due to the increased risk of sudden death. Efficient management remains limited in sub-Saharan Africa because of the limited or unavailable medical resources as automated implantable defibrillator (AID). We report the case of a 56-year old patient with non ischemic dilated cardiomyopathy with very low left ventricular ejection fraction (LVEF)who underwent AID implantation for primary prevention of sudden cardiac death due to ventricular arrhythmias in 2012. Maintenance therapy combined diuretic, angiotensin-converting enzyme (ACE) inhibitor and anti-vitamin K. In the month of November 2014 the patient had iterative episodes requiring the delivery of electric shocks by the AID, without the sensation of palpitations suggestive of episodes of arrhythmias. Clinical examination is a poor screening test, especially for heart failure. AID detected multiple episodes of tachycardia and ventricular fibrillation justifying antitachycardia pacing (ATP) therapy or the delivery of electric shocks of 15J. The patient was treated with amiodarone and beta blocker. Evolution was favorable at 3-months follow-up. The patients had resumed normal activities, without experiencing new episodes requiring the delivery of electric shocks. This study emphasizes the essential role of anti-arrhythmic drug therapy for severe ventricular arrhythmias, even in the presence of AID.

摘要

严重室性心律失常在心力衰竭期间很常见;由于猝死风险增加,它们是一种危及生命的状况。在撒哈拉以南非洲,由于医疗资源有限或无法获得自动植入式除颤器(AID),有效管理仍然受限。我们报告了一例56岁非缺血性扩张型心肌病患者,其左心室射血分数(LVEF)极低,于2012年因室性心律失常接受AID植入以预防心脏性猝死。维持治疗联合使用利尿剂、血管紧张素转换酶(ACE)抑制剂和抗维生素K。2014年11月,患者反复出现发作,需要AID进行电击除颤,但没有提示心律失常发作的心悸感。临床检查作为筛查试验效果不佳,尤其是对于心力衰竭。AID检测到多次心动过速和心室颤动发作,证明有必要进行抗心动过速起搏(ATP)治疗或给予15J电击。患者接受了胺碘酮和β受体阻滞剂治疗。3个月随访时病情好转。患者已恢复正常活动,未再出现需要电击除颤的新发作。本研究强调了抗心律失常药物治疗对严重室性心律失常的重要作用,即使在有AID的情况下也是如此。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8e69/5516655/397520ab288d/PAMJ-27-31-g001.jpg

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