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双侧线状苔藓：一例病例报告并文献复习

Bilateral Lichen Striatus: A Case Report with Review of Literature.

作者信息

Gupta Aastha, Gautam Ram K, Bhardwaj Minakshi

机构信息

Department of Dermatology, Dr. Ram Manohar Lohia Hospital, New Delhi, India.

Department of Pathology, Dr. Ram Manohar Lohia Hospital, New Delhi, India.

出版信息

Indian Dermatol Online J. 2017 Jul-Aug;8(4):264-266. doi: 10.4103/idoj.IDOJ_304_16.

DOI:10.4103/idoj.IDOJ_304_16
PMID:28761844
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5518579/
Abstract

Lichen striatus is a self-limiting dermatosis presenting with sudden eruption of lichenoid papules along the lines of Blaschko. A 5-year-old girl presented with asymptomatic hypopigmented linear lesions over both upper limbs. The histopathological examination revealed spongiosis, vacuolar alteration of the basal layer and lymphocytic exocytosis with a mild-to-moderate perivascular mononuclear infiltrate in the dermis. Lichen striatus was diagnosed based upon the characteristic clinical and histopathological findings. The pathogenetic mechanism of bilateral lichen striatus is unknown at present, however, a somatic mutation in two different clones of cells can be a possibility.

摘要

线状苔藓是一种自限性皮肤病，表现为沿Blaschko线突然出现苔藓样丘疹。一名5岁女孩双上肢出现无症状色素减退性线状皮损。组织病理学检查显示有海绵形成、基底层空泡改变以及淋巴细胞外渗，真皮有轻度至中度血管周围单核细胞浸润。根据特征性的临床和组织病理学表现诊断为线状苔藓。目前双侧线状苔藓的发病机制尚不清楚，不过，两个不同细胞克隆中的体细胞突变是一种可能。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/433e/5518579/f7a9e05990b5/IDOJ-8-264-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/433e/5518579/ab0e72295fb5/IDOJ-8-264-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/433e/5518579/94213fc4eed8/IDOJ-8-264-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/433e/5518579/f7a9e05990b5/IDOJ-8-264-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/433e/5518579/ab0e72295fb5/IDOJ-8-264-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/433e/5518579/94213fc4eed8/IDOJ-8-264-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/433e/5518579/f7a9e05990b5/IDOJ-8-264-g003.jpg

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Post-Inflammatory Hypopigmentation: Review of the Etiology, Clinical Manifestations, and Treatment Options.炎症后色素减退：病因、临床表现及治疗选择综述

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