Rao Medha, Young Katherine, Jackson-Cowan Ladonya, Kourosh Arianne, Theodosakis Nicholas
Department of Dermatology, Massachusetts General Hospital, Boston, MA 02114, USA.
Robert Wood Johnson Medical School, New Brunswick, NJ 08901, USA.
J Clin Med. 2023 Feb 3;12(3):1243. doi: 10.3390/jcm12031243.
Post-inflammatory hypopigmentation is a common acquired pigmentary disorder that is more prominent in skin of color, leading to great cosmetic and psychosocial implications. Often, a diagnosis with a pigmentary disorder can negatively impact an individual's health-related quality of life and may result in stigma. Although most cases of post-inflammatory hypopigmentation resolve spontaneously over time, a systematic diagnostic approach can help with identifying the underlying etiology and informing treatment strategies. It can be due to cutaneous inflammation, sequelae of inflammatory or infectious dermatoses, or dermatologic procedures. Therefore, a thorough understanding of the epidemiology, patient history, physical exam findings, and clinical features of post-inflammatory hypopigmentation phenomenon can explain the primary cause to providers and allow for patient education. It is also important to understand the various therapeutic approaches available and the efficacy of these options, which will inform providers to choose the appropriate therapy for patients. Although algorithms exist for classifying acquired disorders of hypopigmentation, there are no established algorithms for the diagnosis and treatment of post-inflammatory hypopigmentation, which warrants further exploration and discourse.
炎症后色素减退是一种常见的获得性色素沉着障碍，在有色人种皮肤中更为明显，会对容貌和心理社会方面产生重大影响。通常，色素沉着障碍的诊断可能会对个人的健康相关生活质量产生负面影响，并可能导致污名化。尽管大多数炎症后色素减退病例会随着时间自发消退，但系统的诊断方法有助于确定潜在病因并指导治疗策略。它可能是由于皮肤炎症、炎症性或感染性皮肤病的后遗症或皮肤科手术引起的。因此，深入了解炎症后色素减退现象的流行病学、患者病史、体格检查结果和临床特征，可以向医疗人员解释其主要病因，并对患者进行教育。了解现有的各种治疗方法及其疗效也很重要，这将有助于医疗人员为患者选择合适的治疗方法。虽然存在用于分类获得性色素减退障碍的算法，但目前尚无针对炎症后色素减退的诊断和治疗的既定算法，这值得进一步探索和讨论。
