Division of Plastic and Reconstructive Surgery, Department of Surgical Oncology, University Health Network, Toronto, Canada. Anne.O'
Department of Surgery, University of Toronto, Toronto, Canada. Anne.O'
Ann Surg Oncol. 2017 Oct;24(11):3174-3179. doi: 10.1245/s10434-017-6014-0. Epub 2017 Jul 31.
Breast implant-associated anaplastic large cell lymphoma (BIA-ALCL) is a rare disease that has been diagnosed in an extremely small proportion of women with breast implants. The pathogenesis of this disease is currently poorly understood, but it appears to be related to textured implants. Recent high-profile media coverage of this rare clinical entity is likely to cause considerable anxiety for breast cancer patients who have undergone alloplastic breast reconstruction. The purpose of this review is to provide surgical oncologists with an evidence-based overview of the incidence, diagnosis, and management of BIA-ALCL with a particular emphasis on breast reconstruction cases. It is essential that surgical oncologists are familiar with BIA-ALCL, because although it is extremely rare, early recognition and surgical resection will be curative in many cases.
乳房植入物相关间变性大细胞淋巴瘤（BIA-ALCL）是一种罕见疾病，仅在极少数乳房植入物女性中被诊断出。目前，这种疾病的发病机制尚不清楚，但似乎与纹理植入物有关。最近，媒体对这种罕见临床实体的大量报道可能会给接受过乳房假体再造的乳腺癌患者带来相当大的焦虑。本文的目的是为外科肿瘤学家提供 BIA-ALCL 的发生率、诊断和治疗的循证概述，特别强调乳房重建病例。外科肿瘤学家必须熟悉 BIA-ALCL，因为尽管它非常罕见，但在许多情况下，早期识别和手术切除将是治愈的。
