Center for Chronic Pruritus (KCP) and Department of Dermatology, University Medical Center, Münster, Germany.
Institute for Health Care Research in Dermatology and Nursing (IVDP), Competence Center for Nursing Research in Dermatology (CVderm), University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
J Dtsch Dermatol Ges. 2017 Aug;15(8):860-872. doi: 10.1111/ddg.13304.
Associated with a host of different diseases, pruritus is a cardinal symptom that poses an interdisciplinary diagnostic and therapeutic challenge. Over time, that symptom may progress independently of the initial cause, thus losing its function as a warning sign and turning into a clinically relevant disease of its own. In Germany, approximately 13.5 % of the general population are affected by chronic pruritus, with an incidence of 7 %. All forms of chronic pruritus require targeted treatment consisting of (a) diagnosis and management of the underlying disease, (b) dermatological treatment of primary or secondary (for example, dry skin, scratch lesions) symptoms, (c) symptomatic antipruritic treatment, and (d) psychological/psychotherapeutic treatment in case of an underlying or associated psychological or psychosomatic condition. Medical care of patients with chronic pruritus should therefore include an interdisciplinary approach, in particular with respect to diagnosis and therapy of the underlying disease as well as in terms of the management of treatment and adverse events. The objective of the present interdisciplinary guidelines is to define and standardize diagnostic and therapeutic procedures in patients with chronic pruritus. This is a short version of the current S2 guidelines on chronic pruritus. The long version may be found at www.awmf.org.
瘙痒与许多不同的疾病相关，是一个具有挑战性的跨学科诊断和治疗的主要症状。随着时间的推移，该症状可能会独立于初始原因而进展，从而失去其作为警告信号的功能，并转化为自身具有临床相关性的疾病。在德国，约有 13.5%的普通人群受到慢性瘙痒的影响，发病率为 7%。所有形式的慢性瘙痒都需要有针对性的治疗，包括：(a) 潜在疾病的诊断和管理，(b) 原发性或继发性（例如，皮肤干燥、搔抓损伤）症状的皮肤病学治疗，(c) 对症止痒治疗，以及 (d) 在存在潜在或相关心理或身心疾病的情况下进行心理/心理治疗。因此，慢性瘙痒患者的医疗护理应包括跨学科的方法，特别是在潜在疾病的诊断和治疗方面，以及在治疗和不良事件的管理方面。本跨学科指南的目的是定义和标准化慢性瘙痒患者的诊断和治疗程序。这是慢性瘙痒当前 S2 指南的简短版本。长版本可在 www.awmf.org 上找到。
